Hubei Zhongjia Pharmaceutical Co., Ltd.

This product has a broad-spectrum antibacterial effect, especially high antibacterial activity against aerobic Gram-negative bacilli. It has good antibacterial activity in vitro against the following bacteria: most bacteria of the Enterobacteriaceae family, including Citrobacter, Enterobacter cloacae, Enterobacter aerogenes, Escherichia coli, Klebsiella, Proteus, Salmonella, Shigella, Vibrio, Yersinia, etc. It often also has antibacterial activity against multi-drug resistant bacteria. It has high antibacterial activity against penicillin-resistant Neisseria gonorrhoeae, enzyme-producing influenza bacilli and Moraxella. It has antibacterial activity against most strains of Pseudomonas such as Pseudomonas aeruginosa. This product has antibacterial activity against methicillin-sensitive Staphylococcus aureus, and only moderate antibacterial activity against Streptococcus pneumoniae, hemolytic Streptococcus and Enterococcus faecalis. It has good antimicrobial effect against Chlamydia trachomatis, Mycoplasma, Legionella, and also has antibacterial activity against Mycobacterium tuberculosis and atypical mycobacteria. It has poor antibacterial activity against anaerobic bacteria. Ciprofloxacin is a bactericide that acts on the A subunit of bacterial DNA gyrase, inhibiting DNA synthesis and replication, leading to bacterial death.

It combines with pyrophosphate in the body to form a coenzyme, participates in the oxidative decarboxylation reaction of pyruvate and α-ketoglutaric acid in sugar metabolism, and is necessary for sugar metabolism. When it is deficient, oxidation is blocked to form pyruvate and lactic acid accumulation, which affects the body's energy supply. Its symptoms are mainly manifested in the nervous and cardiovascular systems, with multiple peripheral neuritis affecting both sensory nerves and motor nerves, manifested as paresthesia, neuralgia, limb weakness, muscle soreness and atrophy. In terms of cardiovascular, due to the increase of acetone and lactic acid in the blood, the small arteries are dilated, the diastolic pressure is reduced, and the myocardial metabolism is disturbed, so it is easy to have symptoms of heart failure such as palpitations, shortness of breath, chest tightness, cardiac hypertrophy, liver and lung congestion and peripheral edema. In terms of the digestive tract, it is manifested as weakness and weight loss caused by decreased appetite.

Fluconazole is a triazole broad-spectrum antifungal drug that inhibits the reproduction and growth of fungi by highly selectively inhibiting the C-14-alpha;-demethylation of fungal cytochrome P-450 sterols, causing the accumulation of 14-alpha;-methyl sterols in fungi. In vitro tests have shown that this product has antibacterial activity against Cryptococcus neoformans and Candida species. Oral and intravenous injection of fluconazole in animals is effective in the following animal fungal infection models: Candida infection (including systemic candidiasis in immunodeficient animals); Cryptococcus neoformans infection (including intracranial infection); Microsporum and Trichophyton infection, etc. Fluconazole is also effective against Blastomyces dermatitidis infection and Coccidioides immitis infection (including intracranial infection); and is also effective against infections caused by Histoplasma capsulatum in normal animals and immunosuppressed animals.

This product is a glucocorticoid with anti-inflammatory, immunosuppressive, antitoxin and anti-shock effects. (1) Anti-inflammatory effect: It has an effect on inflammation caused by various causes except viruses. Glucocorticoids reduce and prevent tissue response to inflammation, thereby reducing the symptoms of inflammation. They can also inhibit the repair of tissues in the later stages of inflammation and reduce sequelae. (2) Immunosuppressive effect: It prevents or inhibits cell-mediated immune responses, delayed allergic reactions, and reduces the expansion of primary immune responses. (3) Anti-toxic and anti-shock effects: Glucocorticoids can improve the body's tolerance, reduce cell damage, and play a role in protecting the body. It also has the effects of dilating blood vessels, enhancing myocardial contractility, and improving microcirculation.

This product is a fluoroquinolone antibacterial drug with broad-spectrum antibacterial effect