Unspecified

1. It can simultaneously relax the coronary arteries in the normal blood supply area and the ischemic area, antagonize spontaneous or ergonovine-induced coronary artery spasm, increase the delivery of myocardial oxygen to patients with coronary artery spasm, and relieve and prevent coronary artery spasm. 2. It can inhibit myocardial contraction, reduce myocardial metabolism, and reduce myocardial oxygen consumption. 3. It can relax peripheral resistance vessels, reduce peripheral resistance, and can reduce systolic and diastolic blood pressure, reducing cardiac afterload. 4. It can delay the sinus node function and atrioventricular conduction of isolated hearts; electrophysiological studies on whole animals and humans have not found that this product has the effect of delaying atrioventricular conduction, prolonging the recovery time of the sinus node, and slowing down the sinus node rate.

It mainly acts on H2 receptors on parietal cells, competitively inhibiting histamine. It can inhibit basal gastric acid secretion, as well as gastric acid secretion stimulated by food, histamine, pentagastrin, caffeine and insulin.

This product is a highly selective 5-HT3 receptor antagonist. It inhibits the occurrence of nausea and vomiting by antagonizing the 5-HT3 receptors in the central chemoreceptor area and peripheral vagus nerve endings. This product has high selectivity and no adverse reactions such as extrapyramidal reactions and excessive sedation.

Vitamin K is a necessary substance for the liver to synthesize coagulation factors II, VII, IX and X. Vitamin K deficiency can cause synthesis disorders of these coagulation factors, and clinically, bleeding tendency and prolonged prothrombin time can be seen. The exact mechanism by which vitamin K promotes the synthesis of factors II, VII, IX and X has not yet been elucidated. Natural vitamin K includes K1 and K2, which are fat-soluble and their absorption depends on the normal secretion of bile. Artificially synthesized vitamin K includes K3 and K4, the former is sodium bisulfite menadione, and the latter is acetyl menadione, which are water-soluble and do not require the presence of bile for absorption.