Extract from the above information

This product is a phenothiazine antipsychotic, and its mechanism of action is mainly related to its blocking of dopamine receptors (DA2) in the mesolimbic system and mesocortical pathways. It has a blocking effect on dopamine (DA1) receptors, 5-hydroxytryptamine receptors, M-type acetylcholine receptors, and α-adrenaline receptors, and has a wide range of effects. In addition, this product can inhibit the dopamine receptors in the medulla oblongata emetic chemoreceptor area at low doses, and directly inhibit the vomiting center at high doses, producing a strong antiemetic effect. It inhibits the body temperature regulation center and lowers the body temperature. The body temperature can change with changes in the external environment. It blocks the action of peripheral α-adrenaline receptors, dilates blood vessels, causes a drop in blood pressure, and also has a certain effect on the endocrine system.

Not yet clear

Extract from the above information

1. It is an inhibitor of aromatic amino acid decarboxylase; 2. Only the L-isomer of α-methyldopa has antihypertensive activity in humans, and the racemic form (DL-α-methyldopa) requires twice the dose to achieve the same antihypertensive effect; 3. Its antihypertensive effect may be through its active metabolite α-methylnorepinephrine stimulating central inhibitory α-adrenergic receptors and pseudo-neurotransmitters, reducing plasma renin activity, thereby lowering arterial blood pressure; 4. It can reduce the concentrations of serotonin, dopamine, norepinephrine, and methylepinephrine in tissues; 5. It has no direct effect on cardiac function, and usually does not reduce glomerular filtration rate or renal blood flow.