Estrogen drugs. This product is a derivative of estriol. Its pharmacological effects are similar to those of estradiol, but its biological activity is low, so its effect on endometrial proliferation is also weak. It is suitable for estrogen replacement therapy for perimenopausal women. The introduction of cyclopentyl ether at the 3rd position increases its lipophilicity, which is beneficial for intestinal absorption and storage in adipose tissue, and then slowly released to play a long-term effect. The introduction of acetylene at the 17th position enhances the estrogen activity.

It can reduce secondary plantar swelling and systemic secondary lesions in rats with adjuvant arthritis, inhibit carrageenan-induced plantar swelling (acute), agar-induced rat granuloma (subacute) and increased skin permeability in rats caused by 5-HT; it can reduce the urine protein content and alleviate glomerular lesions in rabbits with membranous glomerulonephritis model caused by C-BSA (cationized bovine serum albumin).

Benzodiazepine receptor antagonists, which competitively inhibit the reaction of benzodiazepines with their receptors, thereby specifically blocking their central nervous system effects.