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Yunnan Biovalley Pharmaceutical Co., Ltd.

  • Founded in:

    1999-06-13
  • Country:

    China China
  • Address:

    No. 1, Kangjian Road, Yunnan Mile Industrial Park, Fucheng Subdistrict Office, Mile City, Honghe Hani and Yi Autonomous Prefecture, Yunnan Province
  • Tax NO.:

    915301007134092367
  • Registered Funds:

    124.00007 million yuan
  • Website:

  • Email:

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Clindamycin Hydrochloride Injection
The main ingredient of this product is clindamycin hydrochloride, and its chemical name is 6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-7(S)-chloro-6,7,8-trideoxy-L-threo-α-D-galactoctinopyranoside hydrochloride.
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Clindamycin hydrochloride

This product belongs to the lincomycin antibiotics, which is a derivative of lincomycin. Its antibacterial spectrum is the same as that of lincomycin, and its antibacterial activity is 4 to 8 times stronger than that of lincomycin. It has high antibacterial activity against Gram-positive bacteria such as Staphylococcus (including penicillin-resistant strains), Streptococcus, Corynebacterium diphtheriae, Bacillus anthracis, etc. It also has good antibacterial activity against Gram-negative anaerobic bacteria. Most of the Bacteroides, including Bacteroides fragilis, Fusobacterium, Peptococcus, Peptostreptococcus, and Clostridium perfringens, are highly sensitive to this product. Gram-negative aerobic bacteria, including Haemophilus influenzae, Neisseria, and Mycoplasma, are resistant to this product. There is no cross-resistance between this product and penicillin, chloramphenicol, cephalosporins and tetracyclines, but it has partial cross-resistance with macrolides and complete cross-resistance with lincomycin. The mechanism of action of this product is to bind to the 50S subunit of the bacterial ribosome, prevent the elongation of the peptide chain, and thus inhibit the protein synthesis of bacterial cells. This product is an antibacterial drug, but at high concentrations, it also has a bactericidal effect on certain bacteria.

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This product belongs to the lincomycin antibiotics, which is a derivative of lincomycin. Its antibacterial spectrum is the same as that of lincomycin, and its antibacterial activity is 4 to 8 times stronger than that of lincomycin. It has high antibacterial activity against Gram-positive bacteria such as Staphylococcus (including penicillin-resistant strains), Streptococcus, Corynebacterium diphtheriae, Bacillus anthracis, etc. It also has good antibacterial activity against Gram-negative anaerobic bacteria. Most of the Bacteroides, including Bacteroides fragilis, Fusobacterium, Peptococcus, Peptostreptococcus, and Clostridium perfringens, are highly sensitive to this product. Gram-negative aerobic bacteria, including Haemophilus influenzae, Neisseria, and Mycoplasma, are resistant to this product. There is no cross-resistance between this product and penicillin, chloramphenicol, cephalosporins and tetracyclines, but it has partial cross-resistance with macrolides and complete cross-resistance with lincomycin. The mechanism of action of this product is to bind to the 50S subunit of the bacterial ribosome, prevent the elongation of the peptide chain, and thus inhibit the protein synthesis of bacterial cells. This product is an antibacterial drug, but at high concentrations, it also has a bactericidal effect on certain bacteria.

21462-39-5 34
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