Jiangxi Yintao Pharmaceutical Co., Ltd.

Antibacterial, anti-inflammatory

Antibacterial, anti-inflammatory

Improve immune function

Improve immune function

Improve immune function

Improve immune function

Antibacterial, anti-inflammatory, improve immune function

According to the requirements of the "Non-clinical Drug Research Management Standards" and the relevant guidelines for national preclinical research of new drugs, the product was injected into mice at a dose of 0.8 ml/mouse. No abnormal toxic reaction or death was observed within 48 hours after injection, and the abnormal toxicity test results for mice were qualified; according to the method requirements for the inspection of antihypertensive substances in the appendix of the "Pharmacopoeia of the People's Republic of China", this product was inspected for antihypertensive substances in cats, and the results met the requirements for antihypertensive substances specified in the Pharmacopoeia; according to the requirements of the "Non-clinical Drug Research Management Standards" and the relevant guidelines for national preclinical research of new drugs, the product was tested on healthy white Hautley guinea pigs. The product was injected intraperitoneally, 0.5 ml per guinea pig, once every other day, for 3 consecutive times for sensitization. The results showed that the product had no effect on the activity, food intake, and drinking water of guinea pigs, and had no significant effect on the weight gain of guinea pigs. No abnormal reactions occurred during the test, and no guinea pigs died. The incidence and mortality of allergic reactions were both 0. According to the requirements of the "Non-clinical Research Management Standards for Drugs" and the relevant guidelines for preclinical research of new drugs in the country, the product was intravenously injected into healthy and clean ICR mice at a dose of 100 ml/kg. After administration, no abnormal reactions were observed in male and female mice, and no animal deaths were caused. The maximum dosage for mice is greater than 100 ml/kg.

(1) According to the requirements of the "Non-clinical Drug Research Management Standards" and the relevant guidelines for preclinical research of new drugs in the country, the product was injected into mice at a dose of 0.8 ml/mouse. No abnormal toxic reaction or death was observed within 48 hours after injection. The abnormal toxicity test results for mice were qualified. (2) According to the method requirements for the antihypertensive substance test in the appendix of the "Pharmacopoeia of the People's Republic of China", this product was tested for antihypertensive substances in cats, and the results met the antihypertensive substance requirements specified in the Pharmacopoeia. (3) According to the requirements of the "Non-clinical Drug Research Management Standards" and the relevant guidelines for preclinical research of new drugs in China, the product was injected intraperitoneally into healthy white Hautley guinea pigs, 0.5 ml per guinea pig, once every other day, for 3 consecutive times for sensitization. The results showed that the product had no effect on the activity, food intake, and drinking water of guinea pigs, and had no significant effect on the weight gain of guinea pigs. No abnormal reactions occurred during the test, and no guinea pigs died. The incidence rate and mortality rate of allergic reactions were both 0.4) According to the requirements of the "Non-clinical Drug Research Management Standards" and the relevant guidelines for preclinical research of new drugs in China, the product was injected intravenously into healthy clean-grade ICR mice at a dose of 100 ml/kg. After administration, no abnormal reactions were observed in male and female mice, and no animal deaths were caused. The maximum dosage for mice is greater than 100 ml/kg.

(1) According to the requirements of the "Non-clinical Drug Research Management Standards" and the relevant guidelines for preclinical research of new drugs in the country, the product was injected into mice at a dose of 0.8 ml/mouse. No abnormal toxic reaction or death was observed within 48 hours after injection. The abnormal toxicity test results for mice were qualified. (2) According to the method requirements for the antihypertensive substance test in the appendix of the "Pharmacopoeia of the People's Republic of China", this product was tested for antihypertensive substances in cats, and the results met the antihypertensive substance requirements specified in the Pharmacopoeia. (3) According to the requirements of the "Non-clinical Drug Research Management Standards" and the relevant guidelines for preclinical research of new drugs in China, the product was injected intraperitoneally into healthy white Hautley guinea pigs, 0.5 ml per guinea pig, once every other day, for 3 consecutive times for sensitization. The results showed that the product had no effect on the activity, food intake, and drinking water of guinea pigs, and had no significant effect on the weight gain of guinea pigs. No abnormal reactions occurred during the test, and no guinea pigs died. The incidence rate and mortality rate of allergic reactions were both 0.4) According to the requirements of the "Non-clinical Drug Research Management Standards" and the relevant guidelines for preclinical research of new drugs in China, the product was injected intravenously into healthy clean-grade ICR mice at a dose of 100 ml/kg. After administration, no abnormal reactions were observed in male and female mice, and no animal deaths were caused. The maximum dosage for mice is greater than 100 ml/kg.

1. It can reduce the body temperature of febrile rabbits and has an antipyretic effect; 2. It inhibits the ear swelling of mice caused by croton oil and the foot swelling of rats caused by carrageenan, and inhibits the migration of leukocytes in the peritoneal cavity of rats caused by sodium carboxymethyl cellulose, and has an anti-inflammatory effect; 3. It increases the pain threshold of mice and reduces the number of twisting times, and has an analgesic effect; 4. It excites sweat glands and increases the incidence of sweat points and vacuolar sweat glands on the soles of rats, indicating that it has a sweating effect; 5. It has a strong antibacterial and bactericidal effect on experimental strains of Staphylococcus aureus, type A hemolytic Streptococcus, Pseudomonas aeruginosa, Pneumococcus and Shigella flexneri.

1 Experimental confirmation. This product can reduce the body temperature of fever rabbits and has an antipyretic effect; 2 It can reduce the ear swelling of mice caused by croton oil and the foot swelling of rats caused by carrageenan, and inhibit the migration of peritoneal leukocytes caused by sodium carboxymethyl cellulose, and has an anti-inflammatory effect; 3 It can increase the pain threshold of mice and reduce the number of twisting, and has an analgesic effect; 4 It can stimulate sweat glands and increase the incidence of sweat points and vacuolar sweat glands in the soles of rats, indicating that this product has a sweating effect. 5 It has a strong antibacterial and bactericidal effect on experimental strains of Staphylococcus aureus, type A hemolytic streptococci, Pseudomonas aeruginosa, Pneumococcus and Shigella flexneri.

The bactericidal effect is achieved through cross-linking on the surface of microbial cells or inside proteins. Aldehyde groups react with active groups such as amino (-NH2), imino (-HN) and sulfhydryl (-SH) groups of proteins, acting on the outer cell membrane to change cell permeability, destroy enzyme systems, inhibit DNA and RNA, and destroy bacterial proteins to kill microorganisms.