Glutaraldehyde
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Glutaraldehyde
structure -
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CAS No:
111-30-8
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Formula:
C5H8O2
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Chemical Name:
Glutaraldehyde
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Synonyms:
Pentanedial;Glutaraldehyde;Glutardialdehyde;Glutaric dialdehyde;Glutaric acid dialdehyde;Glutaral;1,5-Pentanedial;Sonacide;Hospex;Aldesan;Glutarex 28;Relugan GT;Relugan GT 50;Sporicidin;Cidex 7;Ucarcide 250;Relugan GTW;Glutaclean;Sterihyde;Bactron K 31;Sterihyde L;Cidex-Dialyzer;Tret-O-Lite XC 102;Biomate 743;Glutohyde;Banicide;Panavirocide;Floperm 665X1;Diglutaric aldehyde;Cleancide 275;Cidex;Cidexplus;Wavicide 01;Piror 850;Surcide G 50;Glu-Cid;Sellatan CF-N;NSC 13392;Aqucar 550;Venno-FF super;Sterisol S;Kcide 850;Permachem OB 5;Biocide G 30;Metricide Plus;Maxicide Plus;5-Oxopentanal;Bioban Eth 1000;T 352;Eimaldehyde;KS 02;Formula H;Ukatan 24;Protectol GA 50;Odycide B 310;Ucarcide 50;Ucarcide 50 Antimicrobial;Ucarcide 250 Antimicrobial;GT 50;G 6257;NovaCide 1125;37245-61-7;79215-57-9;107950-89-0;1428979-54-7;1497435-71-8
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CAS No:
Description
Glutaraldehyde is a colorless liquid with a pungent odor, which readily changes to a glossy polymer. The Odor Threshold is 0.04 ppm (NY) and 0.2 ppm (NJ). It is miscible in water and organic solvents. Glutaraldehyde may be incompatible with strong oxidizers and strong bases. It should be noted that alkaline solutions containing glutaraldehyde may react with alcohol, ketones, amines, hydrazines, and proteins.
Characteristics
34.14000
0.55450
Glutaraldehyde solution is a light yellow liquid. Mixes with water. (USCG, 1999)
0.72 g/cm3
-6 °C
101 °C
71ºC
1.373
Miscible
2-8ºC
0.583mmHg at 25°C
Relative vapour density (air = 1): 3.5
LD50 of 25% soln orally in rats: 2.38 ml/kg; by skin penetration in rabbits: 2.56 ml/kg (Smyth)
Noncombustible Liquid
Not explosive
Pungent odor
Mildly acidic (50% solution)
Safety Information
II
8
UN 2810
3
R22; R23; R34; R42/43
S26-S36/37/39-S45
MA2450000
T
Store only in original container. Well closed. Separated from food and feedstuffs, incompatible materials and amines. Separated from strong oxidizers and strong bases. Keep in a well-ventilated room. Keep in the dark.
Glutaral loses activity within 2 wk after prepn.
P261-P273-P280-P305 + P351 + P338-P310
H302 + H332-H314-H317-H334-H335-H400-H411
Glutaraldehyde Use and Manufacturing
1. Recommended for techniques demanding high purity.
2. Contains variable amounts of polymer.1
3. Cross-linking agent for gelatin,1,2 poly(vinyl alcohol),3 and polyheptapeptides.4
4. Glutaraldehyde is used to disinfect medical and dental equipment. Glutaraldehyde is also used for industrial water treatment and as a preservative.
Computed Properties
Molecular Weight:100.12
XLogP3:-0.5
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:100.052429494
Monoisotopic Mass:100.052429494
Topological Polar Surface Area:34.1
Heavy Atom Count:7
Complexity:51.1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Price Analysis
Drug Function and Efficacy
Glutaraldehyde was originally used as a fixative for pathological specimens. It has the strongest effect when the pH value is 7.5-8.5. It can kill bacterial propagules and spores, fungi, and viruses. Its effect is 2-10 times that of formaldehyde. The mechanism of glutaraldehyde killing microorganisms is that the free aldehyde group combines with the amino group of the cell surface or internal protein or enzyme to cause a series of reactions, leading to the death of the microorganism.
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