Promethazine Hydrochloride Injection

As a histamine H1 receptor antagonist, this product can counteract the capillary dilation caused by allergic reactions, reduce the permeability of capillaries, and relieve wheezing caused by bronchial smooth muscle contraction. This product has a long-lasting antihistamine effect and also has a significant central inhibitory effect, which can increase the effects of anesthetics, analgesics, hypnotics and local anesthetics. This product is mainly metabolized in the liver.

The main ingredients and chemical names of this product are: N, N, a-trimethyl-10H-phenothiazine-10-ethylamine hydrochloride

This product is a colorless clear liquid.

1 Skin and mucous membrane allergy: suitable for long-term and seasonal allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis, urticaria, food allergy, skin scratches. 2 Motion sickness: carsickness, seasickness, airplane sickness. 3 Nausea and vomiting.

Intramuscular injection: Adult dosage (1) Anti-allergic, 25 mg once, repeat after 2 hours if necessary; in case of severe allergy, 25-50 mg can be injected intramuscularly, and the maximum dose should not exceed 100 mg. (2) In special emergency situations, it can be diluted to 0.25% with sterile water for injection and slowly injected intravenously; (3) Antiemetic, 12.5-25 mg, repeat every 4 hours if necessary; (4) Sedative and hypnotic, 25-50 mg once. Common dosage for children (1) Anti-allergic, 0.125 mg/kg per body weight or 3.75 mg/m2 per body surface area, once every 4-6 hours; (2) Anti-vertigo, can be given as needed before bedtime, 0.25-0.5 mg/kg per body weight or 7.5-15 mg/m2 per body surface area. Or once

The main adverse reactions are drowsiness, sleepiness, dry mouth, and occasional gastrointestinal irritation. Extrapyramidal symptoms are prone to occur at high doses. Elderly people often experience dizziness, dementia, mental confusion, and hypotension. A few patients experience excitement, insomnia, palpitations, headaches, tinnitus, blurred vision, and dysuria after taking the drug. Overdose may cause clumsiness, slow reaction, and tremors.

It is contraindicated for newborns and premature infants.

1 This product can enhance the effect of anticholinergic drugs such as atropine. 2 The combined use of sedatives, hypnotics, and antiallergic drugs can increase the inhibitory effect of this product on the central nervous system. 3 When used with ototoxic drugs such as aminoglycoside antibiotics, salicylic acid preparations, and norvancomycin, the symptoms of ototoxicity can be masked and difficult to detect. 4 If used with other drugs at the same time, drug interactions may occur. Please consult a doctor or pharmacist for details.

Keep away from light and store in a sealed container.

2ml:50mg

Tonghua Huaxia Pharmaceutical Co., Ltd.

• Founded in:

  2001-12-25

• Address:

  Liming Industrial Zone, Kuaidamao Town, Tonghua County, Jilin Province

• Tax NO.:

  91220521732563319H

• Registered Funds:

  95 million yuan

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