Trifluoperazine hydrochloride

This product is a phenothiazine antipsychotic. Its antipsychotic effect is related to its blocking of dopamine receptors in the brain, inhibiting dopamine receptors in the emetic chemoreceptor area of the medulla oblongata and directly inhibiting the vomiting center, producing a strong antiemetic effect, but weak sedative and anticholinergic effects.

10-[3-(4-Methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-phenothiazine dihydrochloride.

This product is a sugar-coated tablet, which appears white after removing the sugar coating.

It is used for various types of schizophrenia, has an invigorating and activating effect, and is suitable for the catatonic stupor symptoms and the emotional indifference and behavioral withdrawal symptoms of simple and chronic schizophrenia.

Extrapyramidal reactions are common, such as akathisia, acute dystonia and Parkinson's disease. Long-term and excessive use may cause tardive dyskinesia. Palpitations, insomnia, fatigue, dry mouth, blurred vision, dysuria, constipation, galactorrhea, gynecomastia, menstrual disorders, amenorrhea, etc. may occur. Rarely, drowsiness, restlessness, dizziness, and urinary retention are seen. Allergic rash, leukopenia and malignant syndrome are occasionally seen. Occasionally, it may cause postural hypotension, palpitations or electrocardiogram changes, elevated liver enzyme levels or obstructive jaundice, and epilepsy.

Patients with basal ganglia lesions, Parkinson's disease, Parkinson's syndrome, bone marrow suppression, glaucoma, coma and allergy to phenothiazines.

1. When used in combination with ethanol or other central nervous system depressants, it can enhance the central inhibitory effect. 2. When used in combination with antihypertensive drugs, it can easily cause postural hypotension. 3. When used in combination with sultopride, this product increases the risk of ventricular arrhythmia, and in severe cases, it can cause torsades de pointes arrhythmia. 4. When used in combination with other atropine drugs, adverse reactions are additive.

Keep away from light and store in sealed container.