Berbamine Hydrochloride Tablets

1. Pharmacology: This product is a drug that promotes leukocyte proliferation. It has the effect of stimulating bone marrow cell proliferation, increasing the content of hematopoietic stem cell colony factor, promoting the proliferation of bone marrow hematopoietic stem cells and granulocytes, and differentiating into granulocytes. In addition, this product also has the effects of enhancing body immunity, anti-tuberculosis, vasodilation, anti-myocardial hypoxia, ischemia, and anti-arrhythmia. 2. Toxicology: The LD50 of oral administration of berbamine hydrochloride tablets in mice is 1500MG/KG. In the subacute toxicity experiment of dogs, berbamine hydrochloride was taken orally at 30-120MG/KG/day for a total of 30 days. At the beginning, it was taken orally at 30mg/Kg/day, and then changed to 120mg/Kg/day after 15 days. Anorexia only occurred at a large dose (60mg/Kg/day), but it did not affect the continued administration, and it could be restored after stopping the drug. There were no abnormalities in blood routine, BSP excretion and serum urea nitrogen. In the experiment on rats, the drug was administered 3 times a week, 250 mg/Kg each time, for 5 consecutive months. The weight of the animals was the same as that of the control group, and no abnormal changes were found in the liver, kidneys, spleen, etc. during pathological examination, proving that the long-term toxicity of Berberis hydrochloride is very low.

Berbamine Hydrochloride

This product is a sugar-coated tablet. After removing the sugar coating, it appears off-white, yellowish-white or light yellow. It is odorless and tastes bitter.

It is used for leukopenia caused by various reasons. It can also be used to prevent leukopenia after cancer radiotherapy and chemotherapy.

Oral. 3 times a day, 4 tablets each time; or as directed by your doctor

A few patients experienced headache, weakness, constipation, dry mouth, and paroxysmal abdominal pain and bloating after taking the medicine, but they were able to tolerate the symptoms by continuing to take the medicine. The discomfort symptoms could be relieved or disappeared after taking the medicine for a week. Occasionally, palpitations and coughing occurred.

This product is contraindicated for those who are allergic to it

Combined use with thiosemicarbazide can enhance the anti-tuberculosis efficacy of thiosemicarbazide; it has an additive effect on the anti-cancer efficacy of cyclophosphamide.

Shade, seal, keep in a cool and dry place

28mg

24 months