Scopolamine Butylbromide for Injection

This product is an M cholinergic receptor blocker. Its peripheral effects are similar to those of atropine, with only a slight difference in the degree of action: this product has a stronger antispasmodic effect on smooth muscle than atropine, and can selectively relieve gastrointestinal, bile duct and urinary tract smooth muscle spasms and inhibit their peristalsis. It can also be used to relieve vascular smooth muscle spasms and improve microcirculation; its inhibitory effect on the secretion of glands such as the heart, eye smooth muscle (mydriasis and accommodation paralysis) and salivary glands is weaker than that of atropine. Its central effects mainly include: it has an excitatory effect on the respiratory center; its anti-vertigo and anti-tremor paralysis effects are stronger than atropine; but it has a significant sedative effect on the central nervous system, and a larger dose can produce a hypnotic effect. Therefore, the use of this product rarely causes adverse reactions such as central nervous system excitement, mydriasis, and inhibition of saliva secretion similar to those caused by atropine.

6β,7β-Epoxy-3α-hydroxy-8-butyl-1αH,5αH-tropane (-)-tropate bromide

This product is white or off-white loose mass or powder.

1. Used for preoperative preparation of gastric, duodenal and colon endoscopic examination, endoscopic retrograde pancreatic cholangiography, and gastric, duodenum and colon hypotonic barium radiography or abdominal CT scan, which can reduce or inhibit gastrointestinal motility; 2. Used for gastrointestinal spasm, biliary colic, renal colic or gastrointestinal hypermotility caused by various causes.

Intramuscular injection, intravenous injection or dissolved in 5% glucose injection, 0.9% sodium chloride injection for intravenous drip. Adults take 10-20 mg each time, or take 10 mg once, and then take another 10 mg after an interval of 20-30 minutes.

Reactions such as thirst, visual accommodation disorders, drowsiness, palpitations, facial flushing, nausea, vomiting, dizziness, and headache may occur.

1. Patients with severe heart disease, organic pyloric stenosis or paralytic ileus are prohibited from using this product; 2. Patients who are allergic to this product are prohibited from using this product

Precautions for children: Use with caution in infants and children. Precautions for pregnancy and lactation: Not yet clear. Precautions for the elderly: Before using the drug, the elderly should exclude a history of heart disease and prostate hypertrophy.

1. When used in combination with other anticholinergic drugs, phenothiazines and other drugs, it will increase toxicity; 2. It can antagonize the gastrointestinal motility-promoting effects of metoclopramide, domperidone and other drugs; 3. Certain antiarrhythmic drugs (such as quinidine, disopyramide, etc.) should be used with caution with this product, because the former has the effect of blocking the vagus nerve, so it can enhance the anticholinergic effect of this product, leading to dry mouth, blurred vision, and dysuria. The elderly should pay special attention to this; 4. This product can be used in combination with adrenergic drugs (such as: dextroamphetamine 5mg) to enhance the antiemetic effect and reduce the drowsiness of this product, but the dry mouth is more significant; 5. When used in combination with tricyclic antidepressants (amitriptyline, etc.), both

Keep tightly closed in a cool, dark and dry place.

20mg

24 months

Hainan Shuangcheng Pharmaceuticals Co., Ltd.

• Founded in:

  2000-05-22

• Address:

  No. 16 Xingguo Road, Xiuying District, Haikou City

• Tax NO.:

  9146000072122491XG

• Registered Funds:

  414.68975 million yuan

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