Cyclic Adenosine Monophosphate Injection

Cyclic adenosine monophosphate is a protein kinase activator and a derivative of nucleotides. It is an important substance with physiological activity that is widely present in the human body. It is generated by adenosine triphosphate under the catalysis of adenylate cyclase and can regulate various functional activities of cells. As the second messenger of hormones, it plays a role in regulating physiological functions and material metabolism in cells, can change the function of cell membranes, promote calcium ions in reticulum to enter muscle fibers, thereby enhancing myocardial contraction, and can promote the activity of respiratory chain oxidases, improve myocardial hypoxia, relieve symptoms of coronary heart disease and improve electrocardiograms. In addition, it plays an important role in regulating sugar, fat metabolism, nucleic acid, and protein synthesis.

The main component of this product is cyclic adenosine monophosphate, and its chemical name is: 6-amino-9-B-D-ribofuranosyl-9H-purine-4',5'-cyclic hydrogen phosphate. Chemical structure: Molecular formula: C10H12N5O6P·H2O Molecular weight: 329.21 Excipients L Sodium chloride, phosphate buffer, water for injection.

This product is a colorless clear liquid.

1. Used for angina pectoris, myocardial infarction, myocarditis and cardiogenic shock; 2. It has a certain effect on improving symptoms such as palpitations, shortness of breath and chest tightness in rheumatic heart disease; 3. It can improve the efficacy of acute leukemia combined with chemotherapy, and can also be used to induce remission of acute leukemia; 4. In addition, it also has a certain effect on chronic bronchitis in the elderly, various hepatitis and psoriasis.

For intravenous injection, 20 mg at a time, dissolved in 20 ml of 0.9% sodium chloride injection, bolus injection, twice a day. For intravenous drip, 40 mg of this product is dissolved in 250-500 ml of 5% glucose injection, once a day. Coronary heart disease is treated for 15 days, and can be used continuously for 2-3 courses; leukemia is treated for one month; psoriasis is treated for 2-3 weeks, which can be extended to 4-7 weeks, and the daily dosage can be increased to 60-80 mg.

Fever and rash are occasionally seen. Large doses of intravenous injection (up to 0.5 mg/kg per minute) may cause abdominal pain, headache, myalgia, testicular pain, back pain, limb weakness, nausea, numbness of hands and feet, and high fever.

People who are allergic to this product are prohibited from using it, and those with allergic constitutions should use it with caution.

Precautions for children: This experiment has not been conducted and there is no reliable reference. Precautions for pregnancy and lactation: This experiment has not been conducted and there is no reliable reference. Precautions for the elderly: This experiment has not been conducted and there is no reliable reference.

This experiment has not been conducted and there are no reliable references.

Keep in a dark, airtight container in a cool place (not exceeding 20°C).

2ml:20mg

24 months

Shandong FANGMING Pharmaceutical Group Co., Ltd.

• Founded in:

  2000-07-07

• Address:

  Fangming Section, Huanghe Road, Dongming County, Shandong Province

• Tax NO.:

  91371700724268643E

• Registered Funds:

  216.829902 yuan

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