Methoxsalen Tablets
Function and Efficacy
This product is a photosensitizer. When used in conjunction with sun exposure or black light irradiation, it can produce the following photosensitive activities: increase tyrosinase activity, promote epidermal melanin formation, and prompt melanocytes in hair follicles to move to the epidermis, thereby causing pigmentation on the skin. It is used to treat vitiligo. It has anti-epidermal proliferation effects. It inhibits the proliferation of epidermal cells in diseases such as psoriasis and causes skin lesions to subside.
Ingredients
Methoxsalen.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| 8-MethoxypsoralenIngredients |
This product is a photosensitizer. Using this product in combination with sun exposure or black light irradiation can increase tyrosinase activity, promote the formation of epidermal melanin, and prompt melanocytes in hair follicles to move to the epidermis, thereby causing pigmentation on the skin. It is used to treat vitiligo. It has anti-epidermal proliferation effects and can inhibit the proliferation of epidermal cells in diseases such as psoriasis, causing skin lesions to subside. More |
298-81-7 | 10 |
Appearance
This product is white or off-white tablets.
Indication
Vitiligo, psoriasis.
Usage and Dosage
1 Usage: Oral administration, followed by sun exposure or black light exposure two hours later, at least 2-3 times a week (at least 48 hours apart). 2 Dosage: For vitiligo, calculated at 0.5 mg/kg body weight, the dosage for adults is 25 mg-30 mg each time, 2-3 times a week; for psoriasis, calculated at 0.6 mg/kg body weight, the dosage for adults is 30 mg-35 mg each time, 2-3 times a week. 3 Exposure time: a. Sun exposure (sun exposure), the first exposure time is 15-25 minutes, generally 15 minutes for light skin, 20 minutes for medium skin, and 25 minutes for dark skin. The exposure time can be appropriately increased by 5 minutes for subsequent treatments; b. Black light exposure, the exposure treatment time is half of the time it takes for erythema to appear during exposure.
Adverse Reactions
This product has low toxicity. Due to differences in tolerance to light, some patients may experience photoallergic symptoms such as skin itching and erythema. Usually, the symptoms will gradually alleviate or disappear. Antiallergic drugs can also be taken under the guidance of a doctor. Excessive exposure can cause redness, blisters and other symptoms similar to sunburn. At this time, the drug should be discontinued until the symptoms disappear before use. Adjusting the intensity and duration of exposure during treatment can avoid the occurrence of this symptom. A small number of patients may experience mild nausea, headache and other discomfort reactions after oral administration. Taking it with food or milk, or reducing the dosage, can alleviate the discomfort.
Precautions
1. Patients with severe liver disease are prohibited from using this product. 2. Patients with cataracts or other lens diseases are prohibited from using this product. 3. Patients with photosensitivity diseases such as lupus erythematosus, dermatomyositis, porphyria, polymorphic light eruption, and xeroderma pigmentosum are prohibited from using this product. 4. Patients who are allergic to this product are prohibited from using this product.
Special Population Medication
Precautions for children: Not for use by children under 12 years old. Precautions for pregnancy and lactation: Not for use by pregnant and lactating women. Precautions for the elderly: Not for use by the elderly and infirm.
Drug Interactions
Do not take other photosensitizing drugs during treatment. The use of this product with phenothiazines can aggravate the photochemical damage to the choroid, retina and lens.
Storage
Keep away from light and store in sealed container.
Packaging Specification
10 mg
Validity Period
36 months
Manufacturer
Jiangsu Disainuo Pharmaceutical Co., Ltd.
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Founded in:
2006-10-11 -
Address:
No. 3, Kang'an Road, Liyang Economic Development Zone, Jiangsu Province -
Tax NO.:
91320481792322090C -
Registered Funds:
100 million yuan -
Website:
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Email: