Promethazine Hydrochloride Tablets
Function and Efficacy
As a histamine H1 receptor antagonist, this product can counteract the capillary dilation caused by allergic reactions, reduce the permeability of capillaries, and relieve wheezing caused by bronchial smooth muscle contraction. This product has a long-lasting antihistamine effect and also has a significant central inhibitory effect, which can increase the effects of anesthetics, analgesics, hypnotics and local anesthetics. This product is mainly metabolized in the liver.
Ingredients
The main ingredients and chemical names of this product are: N, N, a-trimethyl-10H-phenothiazine-10-ethylamine hydrochloride
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| Promethazine hydrochlorideIngredients |
As a histamine H1 receptor antagonist, it can counteract capillary dilation caused by allergic reactions, reduce capillary permeability, and relieve wheezing caused by bronchial smooth muscle contraction. It has a long-lasting antihistamine effect and also has a significant central inhibitory effect, which can increase the effects of anesthetics, analgesics, hypnotics, and local anesthetics. It is mainly metabolized in the liver. More |
58-33-3 | 29 |
Appearance
This product is a sugar-coated tablet, which is white or slightly yellow after removing the sugar coating.
Indication
1 Skin and mucous membrane allergy: suitable for long-term and seasonal allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis, urticaria, food allergy, skin scratches. 2 Motion sickness: carsickness, seasickness, airplane sickness. 3 Nausea and vomiting.
Usage and Dosage
1 Allergic rhinitis: Adults, take 10-20 mg (1-2 tablets) orally once a day. Or take according to the doctor's advice. 2 Urticaria, eczema, dermatitis, pruritus, psoriasis, bronchial asthma. Usually adults take 20 mg (2 tablets) orally once a day. Or take according to age and symptoms.
Adverse Reactions
The main adverse reactions are drowsiness, sleepiness, dry mouth, and occasional gastrointestinal irritation. Extrapyramidal symptoms are prone to occur at high doses. Elderly people often experience dizziness, dementia, mental confusion, and hypotension. A few patients experience excitement, insomnia, palpitations, headaches, tinnitus, blurred vision, and dysuria after taking the drug. Overdose may cause clumsiness, slow reaction, and tremors.
Precautions
It is contraindicated for newborns and premature infants.
Special Population Medication
Precautions for children: 1. Anti-allergic, 0.125 mg/kg of body weight or 3.75 mg/m2 of body surface area, once every 4 to 6 hours, or 0.5 mg/kg of body weight or 15 mg/m2 of body surface area before bedtime; calculated by age, daily dose is 5-10 mg for children under 1 year old, 5-15 mg for 1-5 years old, 10-25 mg for those over 6 years old, which can be given once or twice; 2. Anti-emetic, 0.25-0.5 mg/kg of body weight or 7.5-15 mg/m2 of body surface area, once every 4 to 6 hours if necessary, or 10-25 mg, once every 4 to 6 hours if necessary; 3. Anti-dizziness, 0.5 mg/kg of body weight or 15 mg/m2 of body surface area, once every 12 hours if necessary, Precautions for pregnancy and lactation: Not yet clear. Precautions for the elderly: Not yet clear.
Drug Interactions
1 This product can enhance the effect of anticholinergic drugs such as atropine. 2 The combined use of sedatives, hypnotics, and antiallergic drugs can increase the inhibitory effect of this product on the central nervous system. 3 When used with ototoxic drugs such as aminoglycoside antibiotics, salicylic acid preparations, and norvancomycin, the symptoms of ototoxicity can be masked and difficult to detect. 4 If used with other drugs at the same time, drug interactions may occur. Please consult a doctor or pharmacist for details.
Storage
Keep away from light and store in a sealed container.
Packaging Specification
12.5mg
Validity Period
36 months
Manufacturer
Guangxi Dahai Sunshine Pharmaceutical Co., Ltd.
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Founded in:
2012-09-27 -
Address:
No. 1 Shangping Road, Guangxi-ASEAN Economic and Technological Development Zone -
Tax NO.:
91450100054382235D -
Registered Funds:
23.8 million yuan -
Website:
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Email: