Mitiglinide Calcium Tablets
Function and Efficacy
Mitiglinide binds to the sulfonylurea receptors on the pancreatic β-cell membrane, inhibiting the ATP-sensitive K channels on the pancreatic β-cell membrane, causing cell depolarization and increased intracellular Ca2 concentration, thereby promoting insulin secretion and lowering blood sugar.
Ingredients
Mitiglinide calcium. Chemical name: bis[2-(S)-benzyl-4-oxo-4-(cis-perhydroisoindol-2-yl)butyric acid] monocalcium salt dihydrate.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| Mitiglinide calcium dihydrateIngredients |
It binds to the sulfonylurea receptors on the pancreatic β-cell membrane, inhibits the ATP-sensitive K channels on the pancreatic β-cell membrane, causes cell depolarization, and increases the intracellular Ca2 concentration, thereby promoting insulin secretion and lowering blood sugar. More |
207844-01-7 | 8 |
Indication
It can improve the changes in blood sugar after eating in patients with type 2 diabetes, and is used for diabetic patients who have not been effectively treated with food therapy and exercise therapy.
Usage and Dosage
Adults should take 10 mg of mitiglinide calcium tablets orally once before each meal (within 5 minutes), 3 times a day. In addition, the dosage can be increased or decreased according to symptoms.
Adverse Reactions
Symptoms of hypoglycemia (5.6%), as well as digestive system symptoms such as abdominal distension (1.4%), constipation (1.1%), diarrhea 1.1%), and hunger 1.1%).
Precautions
1. It is contraindicated for patients with severe ketosis, diabetic lethargy and pre-lethargy, and type 1 diabetes; 2. It is contraindicated for patients with severe infection, before and after surgery, and with critical trauma; 3. It is contraindicated for patients with a history of allergy to the ingredients of this drug; 4. It is contraindicated for pregnant women and women who may become pregnant.
Special Population Medication
Precautions during pregnancy and lactation: Contraindicated for use by pregnant women or women who may become pregnant.
Drug Interactions
Caution should be exercised when using mitiglinide calcium in combination with the following drugs. Pay attention to monitoring blood sugar levels and reduce or increase the dosage if necessary.
Storage
Seal and store in a dry place
Packaging Specification
10mg
Manufacturer
CHIA TAI Tianqing Pharmaceutical Group Co., Ltd.
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Founded in:
1997-04-16 -
Address:
No. 369, Yuzhou South Road, Lianyungang City, Jiangsu Province -
Tax NO.:
91320000608398264T -
Registered Funds:
890 million yuan -
Website:
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Email: