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Mefenamic acid capsules

Function and Efficacy

This product is a non-steroidal anti-inflammatory analgesic. It has analgesic, antipyretic and anti-inflammatory effects, and its anti-inflammatory effect is relatively strong. Acute toxicity test results: the oral LD50 of rats is 780mg/kg, and the oral LD50 of mice is 630mg/kg.

Ingredients

Mefenamic acid

Name Description Content CAS NO. Manufacturer
Mefenamic acidIngredients

This product is a non-steroidal anti-inflammatory analgesic. It has analgesic, antipyretic and anti-inflammatory effects, and its anti-inflammatory effect is relatively strong. Acute toxicity test results: the oral LD50 of rats is 780mg/kg, and the oral LD50 of mice is 630mg/kg.

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61-68-7 17

Appearance

This product is in the form of capsules.

Indication

It is used for mild and moderate pain, such as pain after dental, obstetric or orthopedic surgery, as well as pain caused by soft tissue injury and bone and joint pain. In addition, it is also used for dysmenorrhea, vascular headache and cancer pain.

Usage and Dosage

Common oral dosage for adults: for analgesia or treatment of dysmenorrhea, start with 0.5g, then continue with 0.25g, once every 6 hours. One course of treatment should not exceed 7 days.

Adverse Reactions

1. Gastrointestinal reactions are common, such as abdominal discomfort, burning sensation in the stomach, loss of appetite, nausea, abdominal pain, diarrhea, and indigestion. Severe cases may cause peptic ulcers. 2. Others: depression, dizziness, headache, irritability, blurred vision, sweating, shortness of breath, difficulty sleeping, etc. Allergic rashes are rare.

Precautions

1. Patients who are allergic to this product and other non-steroidal anti-inflammatory drugs; 2. Patients with inflammatory bowel disease; 3. Patients with active peptic ulcer.

Special Population Medication

Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Not yet clear. Precautions for the elderly: Not yet clear.

Drug Interactions

(1) When used with alcohol or other non-steroidal anti-inflammatory drugs, gastrointestinal side effects increase and there is a risk of ulcers. Long-term use with acetaminophen may increase the toxic side effects on the kidneys. (2) When used with aspirin or other salicylic acid drugs, the efficacy is not enhanced, but the incidence of gastrointestinal adverse reactions and bleeding tendency increases. (3) When used with anticoagulants such as heparin and dicoumarol and platelet aggregation inhibitors, there is an increased risk of bleeding. (4) When used with furosemide, the latter's sodium excretion and hypotensive effects are weakened. (5) When used with verapamil and nifedipine, the blood concentration of this product increases. (6) This product can increase the blood concentration of digoxin. When used together, it is necessary to pay attention to adjusting the dose of digoxin. (7) This product can enhance the effect of oral antidiabetic drugs. (8) When used with antihypertensive drugs, this product may affect the hypotensive effect of the latter. (9) Probenecid can reduce the excretion of this drug, increase its blood concentration, and thus increase its toxicity. Therefore, it is advisable to reduce the dose of this drug when used together. (10) This drug can reduce the excretion of methotrexate, increase its blood concentration, and even reach toxic levels. Therefore, this drug should not be used together with medium or large doses of methotrexate.

Storage

Sealed and stored in a dry place.

Packaging Specification

0.25g

Validity Period

36 months

Manufacturer

Xi'an Bo'ai Pharmaceutical Co., Ltd.

  • Founded in:

    1995-08-17
  • Address:

    Room 30705, Building B, Jinqiao International Plaza, No. 50, Keji Road, High-tech Zone, Xi'an, Shaanxi Province
  • Tax NO.:

    91610000294191358G
  • Registered Funds:

    39.9702 million yuan
  • Website:

  • Email:

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