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Miconazole clobetasol cream

Function and Efficacy

This product is a compound preparation of miconazole nitrate and clobetasol propionate. Miconazole nitrate is an imidazole antifungal drug. It has antibacterial effect and can also be bactericidal at high concentrations; it can inhibit the biosynthesis of fungal ergosterol and other sterols; it acts on the fungal cell membrane, damages the fungal cell membrane and changes its permeability, causing the leakage of important substances in the cell; it can also inhibit the biosynthesis of fungal triglycerides and phospholipids: it can also inhibit the activity of oxidation and peroxidase, causing excessive accumulation of peroxides in the cell, leading to degeneration or necrosis of fungal subcellular structures; it can inhibit the transformation of Candida albicans spores into invasive hyphae. Clobetasol propionate is a highly effective topical corticosteroid with capillary constriction and anti-inflammatory effects.

Ingredients

This product is a compound preparation, its components are miconazole nitrate, clobetasol propionate, etc.

Name Description Content CAS NO. Manufacturer
Miconazole nitrateIngredients

Imidazole antifungal drugs have antibacterial effects and can also have bactericidal effects at high concentrations; they can inhibit the biosynthesis of fungal ergosterol and other sterols; they act on the fungal cell membrane, damaging the fungal cell membrane and changing its permeability, causing the leakage of important intracellular substances; they can also inhibit the biosynthesis of fungal triglycerides and phospholipids; they can also inhibit the activity of oxidation and peroxidase, causing excessive accumulation of peroxides in the cell, leading to degeneration or necrosis of the fungal subcellular structure; for Candida albicans, they can inhibit the transformation of its spores into invasive hyphae.

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22832-87-7 31
Clobetasol propionateIngredients

A highly potent topical corticosteroid with capillary constriction and anti-inflammatory effects.

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25122-46-7 27

Indication

Used for dermatitis, eczema, tinea manuum, tinea cruris and allergic dermatitis caused by fungi

Usage and Dosage

For external use, apply evenly to the affected area 1-2 times a day.

Adverse Reactions

The medication site may produce irritation symptoms such as blisters, erythema, congestion, burning, itching, folliculitis, skin atrophy and thinning, capillary dilation; it may also cause dry skin, hirsutism, atrophic striae, increased susceptibility to infection, etc. Long-term and large-area medication may cause hypercortical syndrome, manifested as hirsutism, acne, moon face, osteoporosis, etc. It may occasionally cause allergic contact dermatitis.

Precautions

1. It is contraindicated for those who are allergic to corticosteroids and imidazoles. 2. It is contraindicated for use on skin folds such as the face, eyes, armpits and groin.

Drug Interactions

Not yet clear.

Storage

Keep in a dark, sealed and cool place

Packaging Specification

Compound

Manufacturer

Xinxiang Huaqing Pharmaceuticals Co., Ltd.

  • Founded in:

    2005-12-19
  • Address:

    South of Bridge No. 21, Xinzheng Highway, Xinxiang City
  • Tax NO.:

    91410700783402195G
  • Registered Funds:

    50 million yuan
  • Website:

  • Email:

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