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Alendronate Sodium Tablets

Function and Efficacy

This product is a bone metabolism regulator, an aminobisphosphonate, which has a strong affinity with hydroxyapatite in the bone. It can enter the hydroxyapatite crystals in the bone matrix. When osteoclasts dissolve the crystals, the drug is released, which can inhibit the activity of osteoclasts and indirectly inhibit bone resorption through osteoblasts. It is characterized by strong anti-bone resorption activity and no bone mineralization inhibition.

Ingredients

The main ingredient of this product is alendronate sodium.

Name Description Content CAS NO. Manufacturer
Alendronate sodiumIngredients

This product is a bone metabolism regulator, an aminobisphosphonate, which has a strong affinity with hydroxyapatite in the bone. It can enter the hydroxyapatite crystals in the bone matrix. When osteoclasts dissolve the crystals, the drug is released, which can inhibit the activity of osteoclasts and indirectly inhibit bone resorption through osteoblasts. It is characterized by strong anti-bone resorption activity and no bone mineralization inhibition.

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121268-17-5 38

Appearance

White flakes.

Indication

1. For the treatment of osteoporosis in postmenopausal women. 2. For the prevention of hip and spinal fractures (vertebral compression fractures).

Usage and Dosage

Take orally with 200 ml of warm water on an empty stomach at least 30 minutes before breakfast, 10 mg at a time, once a day.

Adverse Reactions

The drug is well tolerated after taking it. A small number of patients may experience gastrointestinal reactions, such as nausea, abdominal distension, abdominal pain, etc., occasionally headache, skeletal muscle spasm, etc., and rarely rash or erythema.

Precautions

It is contraindicated for patients with esophageal motility disorders, such as esophageal atony and esophageal stenosis, severe renal damage, and osteomalacia.

Special Population Medication

Precautions for children: Long-term use may affect bone metabolism and should be used with caution. Precautions for pregnancy and lactation: Safety is unclear and should not be used. Precautions for the elderly: In clinical studies, no age-related differences in efficacy and safety were found for this product, or follow the doctor's advice.

Drug Interactions

1. Antacids and cathartics often contain calcium or other metal ions such as magnesium and iron, which may affect the absorption of this drug. 2. Combination with aminoglycosides may induce hypocalcemia.

Storage

seal.

Packaging Specification

10mg (calculated as alendronic acid)

Validity Period

36 months

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