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Phenolamine tablets

Function and Efficacy

The aminopyrine in this product can inhibit the synthesis and release of prostaglandins in the hypothalamus, restore the normal responsiveness of the sensory neurons in the thermoregulatory center, and have an antipyretic effect; at the same time, it also has an analgesic effect by inhibiting the synthesis of prostaglandins, etc. Aminopyrine can also inhibit the synthesis and release of prostaglandins in local tissues of inflammation, stabilize lysosomal enzymes, and affect the phagocytic function of phagocytes to play an anti-inflammatory role. Acetaminophen is a peripheral analgesic. The mechanism of action is to inhibit the synthesis and release of prostaglandins (PGE1) in the thermoregulatory center of the hypothalamus, thereby causing peripheral vasodilation and sweating to achieve an antipyretic effect. At the same time, it can inhibit the effects of PGE1, bradykinin and histamine, etc., increase the pain threshold and produce analgesic effects. Caffeine is a central nervous system stimulant that can excite the cerebral cortex, increase sensitivity to the outside world, and constrict cerebral blood vessels, enhancing the effect of the first two drugs in relieving headaches. Chlorpheniramine maleate has a strong histamine H1 receptor blocking effect, which can alleviate other respiratory symptoms caused by allergies and also has a mild inhibitory effect on the central nervous system.

Ingredients

This product is a compound preparation, its components are: acetaminophen 0.15g, aminopyrine 0.1g, caffeine 30mg, chlorpheniramine maleate 2mg.

Name Description Content CAS NO. Manufacturer
AcetaminophenIngredients

It is a peripheral analgesic. Its mechanism of action is to inhibit the synthesis and release of prostaglandins (PGE1) in the hypothalamic temperature regulation center, thereby causing peripheral vasodilation and sweating to achieve an antipyretic effect. At the same time, it can inhibit the effects of PGE1, bradykinin and histamine, increase the pain threshold and produce analgesic effect.

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103-90-2 68
Chlorphenamine maleateIngredients

It has a strong histamine H1 receptor blocking effect, can alleviate other respiratory symptoms caused by allergies, and also has a mild inhibitory effect on the central nervous system.

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113-92-8 28

Indication

Used for colds, fever, headaches, neuralgia and rheumatism, etc.

Usage and Dosage

Oral administration. 1 tablet at a time, 3 times a day or as directed by your doctor.

Adverse Reactions

The aminopyrine contained in this compound has obvious adverse reactions. Taking aminopyrine may cause vomiting, rash, fever, heavy sweating and stomatitis, etc. In a few cases, it may cause neutropenia, aplastic anemia, exudative erythema, exfoliative dermatitis, glans erosion, etc.

Precautions

1. Patients allergic to aminopyrine, caffeine, and chlorpheniramine maleate are prohibited from using this product. 2. Patients with gastric ulcer are prohibited from using this product. 3. Neonates or premature infants are prohibited from using this product.

Drug Interactions

1 Isoniazid and meprobamate can enhance the efficacy of caffeine, increasing the concentration of the latter in brain tissue by 55%, while the concentration in liver and kidney decreases. 2 Oral contraceptives may slow down the clearance rate of caffeine. 3 Drinking alcohol or taking central nervous system depressants at the same time can enhance the efficacy of antihistamines. 4 This product can enhance the effects of adamantane, anticholinergics, haloperidol, phenoxylates and sympathomimetic drugs. 5 When quinidine is used together with this product, its atropine-like effect is intensified. 6 Taking this product together with tricyclic antidepressants can enhance the efficacy of the latter.

Storage

Keep away from light and store in sealed container.

Packaging Specification

Compound

Manufacturer

Sichuan Friendly Pharmaceutical Co., Ltd.

  • Founded in:

    2000-11-08
  • Address:

    No. 680, Hongpai Road, Dongxing District, Neijiang City
  • Tax NO.:

    915110007208680786
  • Registered Funds:

    35 million yuan
  • Email:

Other Drugs of Sichuan Friendly Pharmaceutical Co., Ltd.

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