Cefoperazone Sodium and Sulbactam Sodium for Injection

This product has good antibacterial effect on Escherichia coli, Klebsiella, Proteus, Salmonella typhi, Shigella, Citrobacter and other Enterobacteriaceae and Pseudomonas aeruginosa. Haemophilus influenzae, Neisseria gonorrhoeae and Neisseria meningitidis are highly sensitive to this product. This product also has a good effect on all groups of streptococci and pneumococci, and has only a moderate effect on Staphylococcus aureus (methicillin-sensitive strains). Cefoperazone has a good effect on most Gram-positive anaerobes and some Gram-negative anaerobes. Cefoperazone mainly inhibits the synthesis of bacterial cell walls. Sulbactam itself has a weak antibacterial effect and is a competitive, irreversible beta-lactamase inhibitor. When used in combination with cefoperazone, it can increase the ability of cefoperazone to resist degradation by multiple beta-lactamases, and produce a significant synergistic effect on cefoperazone.

The main ingredient of this product is pyrilast potassium, and its chemical name is 9-Methyl-3-(1H-tetrazol-5-yl)-4H-pyrido[1,2-a]PYRIMIDIN-4-onepotassium.

This product is a colorless clear liquid.

Allergic conjunctivitis, spring catarrhal conjunctivitis.

Usually, apply 1 drop at a time, twice a day (morning and evening).

Adverse reactions occurred in 50 cases (1.13%) out of a total of 4,424 cases. The main adverse reactions were eye irritation in 16 cases (0.36%), blepharitis in 12 cases (0.27%), eye discharge in 7 cases (0.16%), conjunctival congestion in 6 cases (0.14%), eyelid pain and itching in 5 cases (0.11%), etc. (4th safety periodic report). If these adverse reactions occur, appropriate measures such as discontinuation of the drug should be taken.

none.

Precautions for children: This product has been effectively used to treat infections in infants. However, extensive studies have not been conducted on premature infants and newborns, so this product must be used with caution after weighing the pros and cons before use in newborns and premature infants. Precautions for pregnancy and lactation: Animal experiments have not found that this product harms reproductive capacity and the fetus, but there is still a lack of sufficient controlled research data in humans. Therefore, pregnant women should use this product with caution and only use this product when it is clearly indicated. Cefoperazone and sulbactam can be secreted into breast milk in small amounts, so lactating women should use it with caution. Precautions for the elderly: The elderly have physiological liver and kidney function impairment, so this product should be used with caution and the dosage needs to be adjusted.

Not yet clear.

Sealed and stored at room temperature.

1.5 g (C25H27N908S2 1.0 g and C8H11N05S 0.5 g)

24 months.

Youcare Pharmaceutical Group Co., Ltd.

• Founded in:

  2001-08-14

• Address:

  No. 6, Hongda Middle Road, Beijing Economic and Technological Development Zone, Beijing

• Tax NO.:

  911100007263731643

• Registered Funds:

  450 million yuan

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