Econazole nitrate cream
Function and Efficacy
This product is an azole antifungal drug and a dechlorinated derivative of miconazole. This product has antibacterial effects on Candida, Chromatiaceae, Coccidioides, Histoplasma, Sporothrix, etc., and also has antibacterial activity against Trichophyton, etc. This product has poor effects on Aspergillus, Sporothrix Schenckii, some dark-colored spores, Mucor, etc. This product inhibits the biosynthesis of ergosterol, the main steroid of fungal cell membrane, by interfering with the activity of cytochrome P-450, damaging the fungal cell membrane and changing its permeability, resulting in leakage of important intracellular substances. This product can inhibit the biosynthesis of triglycerides and phospholipids of fungi, inhibit the activity of oxidases and peroxidases, cause the accumulation of hydrogen peroxide in cells, and lead to cell submicrostructure degeneration and cell necrosis. For Candida albicans, it can inhibit the process of transformation from spores to invasive hyphae.
Ingredients
The main ingredients of this product are: Econazole nitrate
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| Econazole nitrateIngredients |
This product is an azole antifungal drug and a dechlorinated derivative of miconazole. This product has antibacterial effects on Candida, Chromatiaceae, Coccidioides, Histoplasma, Sporothrix, etc., and also has antibacterial activity against Trichophyton, etc. This product has poor effects on Aspergillus, Sporothrix Schenckii, some dark-colored spores, Mucor, etc. This product inhibits the biosynthesis of ergosterol, the main steroid of fungal cell membrane, by interfering with the activity of cytochrome P-450, damaging the fungal cell membrane and changing its permeability, resulting in leakage of important intracellular substances. This product can inhibit the biosynthesis of triglycerides and phospholipids of fungi, inhibit the activity of oxidases and peroxidases, cause the accumulation of hydrogen peroxide in cells, and lead to cell submicrostructure degeneration and cell necrosis. For Candida albicans, it can inhibit the process of transformation from spores to invasive hyphae. More |
68797-31-9 | 18 |
Appearance
This product is a milky white ointment with an emulsion base.
Indication
This product is suitable for the treatment of skin candidiasis; it can also be used to treat tinea corporis, tinea cruris, tinea pedis, tinea versicolor, etc.
Usage and Dosage
Topical application: For skin candidiasis and various tinea, apply once in the morning and evening each day, for 2 to 4 weeks; for tinea versicolor, apply once a day.
Adverse Reactions
Some patients experience local irritation and occasionally allergic reactions, manifested as burning sensation, itching, tingling, congestion, etc.
Precautions
It is contraindicated for those who are allergic to this product.
Special Population Medication
Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Use under the guidance of a physician. Precautions for the elderly: Not yet clear.
Drug Interactions
Not yet clear.
Storage
seal
Packaging Specification
1%
Validity Period
24 months
Manufacturer
Guangdong Hengjian Pharmaceutical Co., Ltd.
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Founded in:
1994-02-23 -
Address:
No. 117, Longxi Road, Jiangmen City, Guangdong Province -
Tax NO.:
91440704193959639D -
Registered Funds:
16.98 million yuan -
Website:
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Email: