Cefaclor Dry Suspension
Function and Efficacy
This product is a broad-spectrum semi-synthetic cephalosporin antibiotic. Its activity against penicillinase-producing Staphylococcus aureus, group A hemolytic streptococci, viridans streptococci and Staphylococcus epidermidis is the same as that of cefadroxil, and its antibacterial effect against non-enzyme-producing Staphylococcus aureus and pneumococci is 2 to 4 times stronger than that of cefadroxil. Its activity against Gram-negative bacilli, including Escherichia coli and Klebsiella pneumoniae, is stronger than that of cefadroxil, and is similar to that of cefadroxil. Its activity against Proteus mirabilis, Salmonella and Shigella is stronger than that of cefadroxil. 2.9 to 8 mg/L of this product can inhibit all Haemophilus influenzae, including strains resistant to ampicillin. Moraxella catarrhalis and Neisseria gonorrhoeae are very sensitive to this product. Indole-positive Proteus, Serratia, Acinetobacter and Pseudomonas aeruginosa are all resistant to this product. The mechanism of action of this product is to inhibit the synthesis of bacterial cell walls.
Ingredients
The main chemical component is cefaclor: (6R,7R)-7-[(R)-2-amino-2-phenylacetylamino]-3-chloro-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid monohydrate
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| CefaclorIngredients |
This product is a broad-spectrum semi-synthetic cephalosporin antibiotic. Its activity against penicillinase-producing Staphylococcus aureus, group A hemolytic streptococci, viridans streptococci and Staphylococcus epidermidis is the same as that of cefadroxil, and its antibacterial effect against non-enzyme-producing Staphylococcus aureus and pneumococci is 2 to 4 times stronger than that of cefadroxil. Its activity against Gram-negative bacilli, including Escherichia coli and Klebsiella pneumoniae, is stronger than that of cefadroxil, and is similar to that of cefadroxil. Its activity against Proteus mirabilis, Salmonella and Shigella is stronger than that of cefadroxil. 2.9 to 8 mg/L of this product can inhibit all Haemophilus influenzae, including strains resistant to ampicillin. Moraxella catarrhalis and Neisseria gonorrhoeae are very sensitive to this product. Indole-positive Proteus, Serratia, Acinetobacter and Pseudomonas aeruginosa are all resistant to this product. The mechanism of action of this product is to inhibit the synthesis of bacterial cell walls. More |
53994-73-3 | 29 |
Appearance
This product is a powder with flavoring.
Indication
This product is mainly suitable for respiratory system, urinary system, ENT, skin and soft tissue infections caused by sensitive bacteria.
Usage and Dosage
Oral administration. Adults: 0.25g once, 3 times a day. For patients with severe infection, the dose can be doubled, but the total amount per day should not exceed 4g. Or follow the doctor's advice. Children: 20-40mg/kg per day, divided into 3 doses, but the total amount per day should not exceed 1g.
Adverse Reactions
1. Common gastrointestinal reactions: soft stools, diarrhea, stomach discomfort, loss of appetite, nausea, vomiting, heating, etc. 2. Serum sickness-like reactions are more common than other antibiotics, especially in children, with typical symptoms including skin reactions and joint pain. 3. Allergic reactions: rash, urticaria, eosinophilia, vulvar itching, etc. 4. Others: mild increase in serum aminotransferase, urea nitrogen and creatinine, proteinuria, tubular urine, etc.
Precautions
Patients who are allergic to this product or other cephalosporins are contraindicated.
Special Population Medication
Precautions for children: The safety of the drug for newborns has not yet been determined. Precautions for pregnancy and lactation: 1. Pregnant women should use with caution. 2. This product can be excreted through breast milk, so lactating women should use it with caution or stop breastfeeding. Precautions for the elderly: Elderly patients should adjust the dosage or medication interval according to their renal function under the guidance of a physician.
Drug Interactions
1. Furosemide, ethacrynic acid, bumetanide and other strong diuretics, carmustine, streptozocin and other antineoplastic drugs and aminoglycoside antibiotics and other nephrotoxic drugs combined with this product may increase nephrotoxicity. 2. Clavulanic acid can enhance the antibacterial activity of this product against certain Gram-negative bacteria that are resistant to this product due to the production of beta-lactamase. 3. Oral administration of probenecid can delay the excretion of this product.
Storage
Protect from light, seal tightly, and store in a cool and dry place.
Packaging Specification
Calculated as C15H14ClN3O4S 1.5 g
Validity Period
24 months
Manufacturer
Hainan Sanye Pharmaceutical Factory Co., Ltd.
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Founded in:
1989-01-19 -
Address:
No. 6, Sanye East Road, Longhua District, Haikou City, Hainan Province -
Tax NO.:
914600002012496387 -
Registered Funds:
10 million yuan -
Email: