Sodium norcantharinate injection

According to literature reports, in vitro tests of this product have a destructive or inhibitory effect on the morphology or proliferation of cell lines such as liver cancer, esophageal cancer, laryngeal cancer, lung cancer, and cervical cancer. In vivo tests, it has a certain inhibitory effect on mouse Ehrlich ascites carcinoma, sarcoma-180, and solid liver cancer. It can increase the respiratory control rate and lysosomal enzyme activity of mitochondria in ascites liver cancer H22 mouse cancer cells, interfere with cancer cell division, block in the M phase, and affect its cycle speed. This product can destroy the skeleton of cancer cells (microfilaments, microtubules), affect the ultrastructure of cancer cells, and cause damage to mitochondria, microvilli, and plasma membranes. It can inhibit DNA synthesis of cancer cells, but it does not inhibit normal bone marrow cells, and can increase white blood cells.

Chemical name: The main ingredients of this product are sodium norcantharidin, 1,2-cis-3,6-oxo-hexahydrophthalic acid sodium salt. Chemical structure: Molecular formula: C8H8O5Na2 Molecular weight: 230.14

This product is a colorless clear liquid.

This product can be used for liver cancer, esophageal cancer, stomach and cardia cancer, lung cancer, and leukopenia. It can also be used as a preoperative medication for cancer or in combined chemotherapy.

1. Intravenous injection. Dilute with 5% glucose injection and slowly push intravenously. 10-30 mg at a time or follow the doctor's advice. Add 250-500 ml of 5% glucose injection and slowly drip it during intravenous drip. 2. Hepatic artery catheterization. 10-30 mg at a time, twice a day. One month is a course of treatment, generally lasting 2-3 courses. 3. Intratumoral injection. 10-30 mg at a time, once a week, 4 times as a course of treatment, which can last for 4 courses.

If the single injection dose exceeds 30 mg, some patients may experience gastrointestinal symptoms such as nausea and vomiting.

1. It is forbidden for those who are allergic to this product; 2. The dosage for children should be reduced as appropriate, generally 25%~50% of the adult dosage, and can be used under the guidance of a doctor; 3. Pregnant women and breastfeeding women should use the drug under the guidance of a doctor and at their discretion.

Precautions for children: The dosage for children should be reduced, generally 25% to 50% of the adult dosage, and should be used under the guidance of a doctor. Precautions for pregnancy and lactation: Pregnant women and lactating women should use the drug under the guidance of a doctor and as appropriate. Precautions for the elderly: This experiment has not been conducted and there is no reliable reference literature.

This experiment has not been conducted and there are no reliable references.

Keep tightly closed.

2ml:10mg (based on norcantharidin)

Tentative 24 months