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Vitamin B6 tablets

Function and Efficacy

Vitamin B6 is converted into pyridoxal phosphate in red blood cells and acts as a coenzyme in various metabolic functions of proteins, carbohydrates, and lipids. Vitamin B6 is also involved in the conversion of tryptophan into niacin or 5-hydroxytryptamine.

Ingredients

Vitamin B6

Name Description Content CAS NO. Manufacturer
Vitamin B6Ingredients

It is converted into pyridoxal phosphate in red blood cells and acts as a coenzyme in various metabolic functions of proteins, carbohydrates, and lipids. It is also involved in the conversion of tryptophan into niacin or 5-hydroxytryptamine.

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8059-24-3 13

Appearance

This product is white tablets.

Indication

1. Applicable for the prevention and treatment of vitamin B6 deficiency (vitamin B6 deficiency can cause xanthine aciduria, sideroblastic anemia, nervous system lesions, seborrheic dermatitis and chapped lips), prevention and treatment of isoniazid poisoning; can also be used for radiation sickness during pregnancy and vomiting and seborrheic dermatitis caused by anticancer drugs. 2. Vitamin B6 supplementation for total parenteral nutrition and malnutrition caused by insufficient intake and progressive weight loss. 3. Treatment of infantile convulsions or administration to pregnant women to prevent infantile convulsions. 4. Leukopenia.

Usage and Dosage

Oral administration: 1. Adults: (1) Vitamin B6 dependence syndrome: 30-600 mg per day at the beginning, 50 mg per day for maintenance, lifelong use. (2) Vitamin B6 deficiency: 10-20 mg per day for 3 weeks, then 2-3 mg per day for several weeks. (3) Congenital metabolic disorders (cystathionuria, hyperoxaluria, homocystinuria, xanthine aciduria): 100-500 mg per day. (4) Drug-induced vitamin B6 deficiency: ① Prevention: 10-50 mg per day (when using penicillamine), or 100-300 mg per day (when using cycloserine, ethionamide or isoniazid). ② Treatment: 50-200 mg per day for 3 weeks, then 25-100 mg per day. (5) Hereditary sideroblastic anemia: 200-600 mg per day for 1-2 months, then 30-50 mg per day, lifelong use. (6) Alcoholism: 50 mg per day. 2. Children: (1) Vitamin B6 dependence syndrome: Infant maintenance dose, 2-10 mg per day, lifelong application, children over 1 year old use the same dosage as adults. (2) Vitamin B6 deficiency: 2.5-10 mg per day for 3 weeks, then 2-5 mg per day for several weeks.

Adverse Reactions

Vitamin B6 is almost non-toxic when renal function is normal. If 200 mg is taken daily for more than 30 days, vitamin B6 dependence syndrome has been reported. 2 to 6 g of vitamin B6 taken daily for several months can cause severe neurosensory abnormalities, progressive gait instability, numbness of the feet, and inflexibility of the hands, which can be relieved after stopping the drug, but still weak.

Precautions

Not yet clear.

Special Population Medication

Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Pregnant women who take large amounts of vitamin B6 may cause vitamin B6 dependence syndrome in newborns. Normal intake of vitamin B6 by nursing mothers has no adverse effects on infants. Precautions for the elderly: Not yet clear.

Drug Interactions

1. Chloramphenicol, cycloserine, ethionamide, nicotinic acid hydralazine, immunosuppressants including adrenocortical hormones, cyclophosphamide, cyclosporine, isoniazid, penicillamine and other drugs can antagonize vitamin B6 or increase the renal excretion of vitamin B6, which can cause anemia or peripheral neuritis. 2. The dosage of vitamin B6 should be increased when taking estrogen. 3. The combination of levodopa and a small dose of vitamin B6 (5 mg per day) can antagonize the anti-tremor effect of levodopa.

Storage

Keep away from light and store in sealed container.

Packaging Specification

10 mg

Validity Period

36 months

Manufacturer

NORTHEAST Pharmaceutical Group Shenyang NO.1 Pharmaceutical Co., Ltd.

  • Founded in:

    1989-01-25
  • Address:

    No. 8 Kunming Lake Street, Shenyang Economic and Technological Development Zone
  • Tax NO.:

    91210106242656694M
  • Registered Funds:

    80 million yuan
  • Website:

  • Email:

Other Drugs of NORTHEAST Pharmaceutical Group Shenyang NO.1 Pharmaceutical Co., Ltd.

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