Compound Bifendate Granules

Bifendate is an intermediate in the synthesis of Schisandra chinensis propyl. Oral administration of 150-200 mg/kg of this product to mice can reduce liver damage and elevated alanine aminotransferase (ALT) caused by carbon tetrachloride. It has an inhibitory effect on liver microsomal lipid peroxidation caused by carbon tetrachloride and the metabolic conversion of carbon tetrachloride into carbon monoxide, and reduces the consumption of reduced coenzyme II and oxygen in the metabolic process of carbon tetrachloride, thereby protecting the structure and function of the hepatocyte biomembrane. This product can also reduce the increase of liver ALT induced by prednisone and promote liver regeneration in mice with partial hepatectomy. The enzyme-lowering effect of this product does not directly inhibit the activity of serum and liver ALT, nor does it accelerate the inactivation of ALT in the blood, which may be a reflection of the reduction of liver tissue damage. This product has a significant induction effect on the activity of cytochrome P450 enzymes, thereby enhancing the detoxification ability of carbon tetrachloride and certain carcinogens. It has an effect on improving protein metabolism in some hepatitis patients, increasing albumin and reducing globulin. It has no negative conversion effect on HbsAg and HbeAg, and cannot shrink the enlarged liver and spleen. Inosine is the precursor of adenine. It can directly penetrate the cell membrane and enter the cell, and then be converted into inosinic acid and adenosine triphosphate. It participates in the energy metabolism and protein synthesis of liver cells, improves the activity of various enzymes, especially coenzyme A and pyruvate oxidase, activates liver function, and promotes the recovery of damaged liver. Vitamin C is involved in the formation of antibodies and collagen, tissue repair (including certain redox effects), the metabolism of phenylalanine, tyrosine, and folic acid, the utilization of iron and carbohydrates, the synthesis of fat and protein, and the maintenance of immune function.

This product is a compound preparation, and its components are 15 mg of bifendate, 100 mg of inosine, and 50 mg of vitamin C in each bag.

This product is light yellow granules with sweet taste.

Used for patients with chronic persistent hepatitis accompanied by elevated alanine aminotransferase (ALT).

Oral administration: 10g each time, 3 times a day, children can take a reduced dose or follow the doctor's advice.

No adverse reactions have been reported.

1. It is contraindicated for those who are allergic to this product. 2. It is contraindicated for those with liver cirrhosis. 3. It is contraindicated for pregnant women and breastfeeding women.

Precautions for children: Reduce the dosage for children. Precautions for pregnancy and lactation: Pregnant and lactating women are prohibited. Precautions for the elderly: Elderly patients should use this product with caution.

Not yet clear.

Sealed and stored in a cool place.

Compound

Tentative 24 months

Jinzhou Bentian Pharmaceutical Co., Ltd.

• Founded in:

  2004-08-24

• Address:

  No. 8, Section 3, Longxiwan Avenue, Niangniang Palace, Binhai New Area, Jinzhou, Liaoning Province

• Tax NO.:

  91210700765420795E

• Registered Funds:

  50 million yuan

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