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L-Ascorbic acid

L-Ascorbic acid structure

CAS No:
50-81-7
Formula:
C6H8O6
Chemical Name:
L-Ascorbic acid
Synonyms:
L-Ascorbic acid;Allercorb;Antiscorbic vitamin;Antiscorbutic vitamin;Ascorbajen;Ascorin;Ascorteal;Ascorvit;Cantan;Cantaxin;Catavin C;Cebicure;Cebione;Cecon;Cegiolan;Ceglion;Celin;Ce-Mi-Lin;Cenetone;Cereon;Cergona;Cescorbat;Cetemican;Cevalin;Cevatine;Cevex;Cevimin;Ce-Vi-Sol;Cevitamic acid;Cevitamin;Cevitan;Cevitex;Ciamin;Cipca;Concemin;Davitamon C;3-keto-L-Gulofuranolactone;L-3-Keto-threo-hexuronic acid lactone;Laroscorbine;Lemascorb;Liqui-Cee;3-Oxo-L-gulofuranolactone;Planavit C;Proscorbin;C-Quin;Ribena;Secorbate;Vicelat;Vicin;Vitacimin;Vitacin;Vitamin C;Vitamisin;Vitascorbol;Redoxon;Vitacee;L-threo-Hex-2-enonic acid,γ-lactone;Ascorbic acid;L-Lyxoascorbic acid;Xyloascorbic acid,L-;Cevital;L-Xyloascorbic acid;C-Vimin;Testascorbic;Adenex;Hybrin;Cetamid;Colascor;Scorbu C;Xitix;Celaskon;Cebion;Cemagyl;Ascorbutina;Viforcit;Vitace;IDO-C;Viscorin;Ascoltin;Hicee;Neo-Valdrin;(+)-Ascorbic acid;Citrovit;Chewcee;L-threo-Ascorbic acid;Ronotec 100;L-(+)-Ascorbic acid;Rontex 100;Juvamine;Rovimix C;Vasc;P 1110;VC 97;Kangbingfeng;Suncoat VC 40;Viscorin 100M;Cewin;Ceklin;Ascorbicap;Cetane;Cetane-Caps TC;Cetebe;E 300;NSC 218455;NSC 33832;Cell C;Ascorell;C-L 6/PW;VC 40;100M;Cinal;Rovimix C-EC;Vitashure 160;Cevarol;Tanvimil C;Vaginorm-C;Monovitan C;Pascorbin;Ascorbalox;Energil C;Bovi-C;Emvit-C;Novasol Cof;5-(1,2-Dihydroxyethyl)-3,4-dihydroxy-5H-furan-2-one;14536-17-5;30208-61-8;50976-75-5;56172-55-5;56533-05-2;57304-74-2;57606-40-3;88845-26-5;89924-69-6;129940-97-2;154170-90-8;259133-78-3;623158-95-2;882690-91-7;884381-69-5;885512-24-3;896436-13-8;1018124-03-2;1129294-89-8;1428525-25-0;1703051-92-6
Categories:
Cosmetic Ingredient > Antioxidant Ingredient

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Description

L-Ascorbic acid is an effective reducing agent and donor antioxidant.

L-Ascorbic acid Basic Attributes

Molecular Weight：

176.124

Exact Mass：

176.12

EC Number：

200-066-2

HScode：

29362700

Characteristics

PSA：

107.22

XLogP3：

-1.4074

Appearance：

White to very light yellow crystalline powder

Density：

1.65 g/cm³

Melting Point：

190-192 °C (decomp)

Boiling Point：

415.8ºC at 760 mmHg

Flash Point：

180.4ºC

Refractive Index：

21 ° (C=10, H2O)

Water Solubility：

H2O: 333 g/L (20 ºC)

Storage Conditions：

Ventilation low temperature drying

Vapor Pressure：

9.28X10-11 mm Hg at 25 deg C (est)

Toxicity：

LD50 oral in rat: 11900mg/kg

Specific rotation：

[α]D/20 between + 20,5° and + 21,5° (10 % w/v aqueous solution)

Explosive limit：

Dust forms explosible mixtures in air with moderate explosion severity.

Odor：

Odorless

Taste：

Pleasant, sharp, acidic taste

PH：

Between 2,4 and 2,8 (2 % aqueous solution)

PKA：

4.7(at 10 °C)

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

R20/21/22

safety instructions：

S24/25

RTECS Number：

CI7650000

Marks：

Storage features：

Separated from strong oxidants and strong bases.

Stability/Shelf Life：

Stable. May be weakly light or air sensitive. Incompatible with oxidizing agents, alkalies, iron, copper.

Precautionary statement(s)：

P264, P280, P302+P352, P305+P351+P338, P321, P332+P313, P337+P313, P362

Hazard Statements：

H315

L-Ascorbic acid Use and Manufacturing

Methods of Manufacturing

Glucose is hydrogenated to N-sorbitol under the catalysis of nickel and then fermented with acetic acid mold at 30 to 34 ° C and Ph value of 5.2 to 5.5 to form L-sorbose. In the presence of fuming sulfuric acid and -8 ℃, L-sorbose and acetone condensation of diacetone sorbose; in the nickel sulfate catalytic and 75 ~ 80 ℃, and then sodium hypochlorite oxidation to produce diacetone-2-keto-L , Gulonic acid; finally hydrolyzed under acidic conditions to produce 2-keto-L-gulonic acid; and then get ascorbic acid.

Uses

1. Antiscorbutic, antiviral
2. Analgesic, antipyretic
3. Physiological antioxidant. Coenzyme for a number of hydroxylation reactions; required for collagen synthesis. Widely distributed in plants and animals. Inadequate intake results in deficiency syndromes such as scurvy. Used as antimicrobial and antioxidant in foodstuffs.

Computed Properties

Molecular Weight:176.12
XLogP3:-1.6
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:176.03208797
Monoisotopic Mass:176.03208797
Topological Polar Surface Area:107
Heavy Atom Count:12
Complexity:232
Defined Atom Stereocenter Count:2
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Material

Oxalic acid

Sorbitol

Sodium erythorbate

Hydrochloric acid

Sodium hypochlorite

Nickel sulfate (NiSO4)

Downstream Products

Butanal

Carbon dioxide

Hydrogen

Lauric acid

Oxalic acid

Thiabendazole

Acetic acid

Hydrogen peroxide

Isobutyraldehyde

Furfural

Price Analysis

Make your L-Ascorbic acid purchase based on the price and market insights! ECHEMI provides professional market insights with prices for you to make a better choice. Learn more on L-Ascorbic acid prices .

Data: 2026-08-13
Price: 19.00Yuan/kg
Change: 0

Drug Function and Efficacy

It participates in amino acid metabolism, synthesis of neurotransmitters, synthesis of collagen and tissue cell interstitial, can reduce the permeability of capillaries, accelerate blood coagulation, stimulate coagulation function, promote iron absorption in the intestine, promote the decrease of blood lipids, increase resistance to infection, participate in detoxification function, and has antihistamine effect and prevents the formation of carcinogens (nitrosamines).

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Vitamin C Injection
Ingredients	The main ingredient of this product is vitamin C, chemical name: L-ascorbic acid. The auxiliary materials are: sodium bicarbonate, sodium metabisulfite, cysteine hydrochloride, disodium edetate.
Indication	1. Large doses of vitamin C can interfere with the anticoagulant effect of anticoagulants. 2. When used in combination with barbiturates or primidone, it can increase the excretion of vitamin C. 3. Sodium cellulose phosphate can promote the metabolism of vitamin C into oxalate. 4. When vitamin C is used for a long time or in large quantities, it can interfere with the effect of disulfiram on ethanol. 5. Salicylic acid can increase the excretion of vitamin C. 6. It should not be used in combination with alkaline drugs (such as aminophylline, sodium bicarbonate, sodium glutamate, etc.), riboflavin, chlorobutanol, copper, and iron ion (trace) solutions to avoid affecting the efficacy. 7. When used in combination with vitamin K3, because the latter is oxidizing, it can produce a redox reaction, which will weaken or eliminate the efficacy of both.
Specifications	20ml:2.5g

Vitamin C Injection
Ingredients	The main ingredient of this product is vitamin C, chemical name: L-ascorbic acid. The auxiliary materials are: sodium bicarbonate, sodium metabisulfite, cysteine hydrochloride, disodium edetate.
Indication	1. Large doses of vitamin C can interfere with the anticoagulant effect of anticoagulants. 2. When used in combination with barbiturates or primidone, it can increase the excretion of vitamin C. 3. Sodium cellulose phosphate can promote the metabolism of vitamin C into oxalate. 4. When vitamin C is used for a long time or in large quantities, it can interfere with the effect of disulfiram on ethanol. 5. Salicylic acid can increase the excretion of vitamin C. 6. It should not be used in combination with alkaline drugs (such as aminophylline, sodium bicarbonate, sodium glutamate, etc.), riboflavin, chlorobutanol, copper, and iron ion (trace) solutions to avoid affecting the efficacy. 7. When used in combination with vitamin K3, because the latter is oxidizing, it can produce a redox reaction, which will weaken or eliminate the efficacy of both.
Specifications	2ml:0.5g
Manufacturer	Fujian Gutian Pharmaceutical Co., Ltd.

Compound Rutin Tablets
Ingredients	This product is a compound preparation, its components are: rutin and vitamin C
Indication	Not yet clear
Manufacturer	Guangxi Zhuang Autonomous Region Drug Research Institute Co., Ltd.

See More Related Drugs

Registered Holders

ANMOL CHEMICALS PRIVATE LTD

United States
Active
Amoli Organics Pvt Ltd

United States
Active
MCGUFF PHARMACEUTICALS INC

United States
Active

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