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Yanhuning for injection

Function and Efficacy

This product is an extract of the plant Andrographis paniculata - andrographolide, which is refined through esterification, dehydration and salt formation to form dehydrated andrographolide succinic acid half-ester potassium sodium salt. It is the same substance as the active metabolite of Andrographolide in the body. Non-clinical pharmacological studies of andrographolide have shown that: 1. This product has a strong antipyretic effect on rabbits with fever caused by bacterial endotoxins, can promote the disappearance of fever, and the effect is rapid and can last for more than 4 hours; 2. This product can counteract the increased permeability of capillary walls caused by xylene or histamine; 3. This product can shorten the sleep latency of mice caused by sodium pentobarbital, prolong their sleep time, and can also enhance the effect of subthreshold sodium pentobarbital to induce sleep in mice. The test results indicate that this product has a significant sedative effect; 4. This product can significantly promote the adrenal cortex function of rats and increase the body's emergency response to pathogen infection; 5. Clinical etiological diagnosis experiments and tissue culture inactivation experiments show that this product has a certain inactivation effect on influenza virus type AⅠ, type AⅢ, pneumonia adenovirus (Adv) type III, type IV, and enterosyncytial virus (Rsv) in vitro.

Ingredients

Yan Hu Ning.

Name Description Content CAS NO. Manufacturer
PotassiuM sodiuM Dehydroandrographolide SuccinateIngredients

This product is a potassium sodium salt of dehydrated andrographolide succinate half ester made by esterification, dehydration and salt formation of andrographolide, which is the same substance as the active metabolite of Andrographolide in the body. It has antipyretic, anti-inflammatory and sedative effects, can promote the disappearance of fever, counteract the increased permeability of capillary walls caused by xylene or histamine, has a significant sedative effect, and can also significantly promote the adrenal cortex function of rats and increase the body's emergency response to pathogen infection; it has a certain inactivation effect on influenza virus type AⅠ, type AⅢ, pneumonia adenovirus (Adv) type Ⅲ, type Ⅳ, and enterosyncytial virus (Rsv) in vitro.

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Appearance

This product is white or slightly yellow powder or lump.

Indication

1. Respiratory tract infection: viral pneumonia, pneumonia; acute pharyngitis, tonsil fire; acute and chronic bronchitis; 2. Gastrointestinal infection: viral enteritis; acute dysentery; rotavirus-induced diarrhea; 3. Urinary tract infection: acute pyelonephritis, cystitis; urinary tract infection; 4. Emergency department application: fever, influenza and respiratory tract, gastrointestinal tract, urinary tract and other infections caused by viruses; 5. Otorhinolaryngology application: otitis media; sinusitis; rhinitis; 6. Other applications: treatment of cancer fever; inhibition of tumor cell growth; improvement of myocardial ischemia and myocarditis symptoms; treatment of jaundice, hepatitis, sexually transmitted diseases, etc.

Usage and Dosage

Before use, add an appropriate amount of sterile injection water to dissolve. Intramuscular injection: 40-80 mg once, 1-2 times a day. For intravenous drip, dilute with 5% glucose injection or 5% glucose sodium chloride injection and drip 0.16-0.4 g once, 1-2 times a day.

Adverse Reactions

Allergic reactions such as rash may occur occasionally.

Precautions

1. Those who are allergic to this product are prohibited from using this product. 2. Pregnant women are prohibited from using this product.

Special Population Medication

Precautions for children: Reduce dosage for children or follow doctor's advice. Precautions for pregnancy and lactation: This product has cytotoxic effects on placental chorionic trophoblast cells, and animal tests show that it has anti-early and mid-pregnancy effects, so it is contraindicated for pregnant women. Precautions for the elderly: Use with caution or follow doctor's advice.

Drug Interactions

This product should not be used in combination with acidic or alkaline drugs or drugs containing sodium bisulfite or sodium pyrosulfite as antioxidants. This product should not be used in combination with aminoglycosides or quinolones.

Storage

Keep tightly closed in a cool, dry place.

Packaging Specification

80mg

Validity Period

One year

Manufacturer

Hubei Changlian Dule Pharmaceutical Co., Ltd.

  • Founded in:

    2000-04-24
  • Address:

    No. 180, Yixing Avenue, Yiling District, Yichang City, Hubei Province
  • Tax NO.:

    914205066764994030
  • Registered Funds:

    73.460277 yuan
  • Email:

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