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Meloxicam Capsules

Function and Efficacy

This product is an enolic acid nonsteroidal anti-inflammatory drug (NSAID) with strong anti-inflammatory, analgesic and antipyretic effects. It can inhibit the synthesis of prostaglandins and selectively inhibit cyclooxygenase-2 (COX-2), making it safer than other NSAIDs.

Ingredients

The main ingredient of this product is meloxicam, whose chemical name is 4-hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2H-1,2-benzothiazine-3-carboxamide-1,1,-dioxide.

Name Description Content CAS NO. Manufacturer
MeloxicamIngredients

This product is an enolic acid nonsteroidal anti-inflammatory drug (NSAID) with strong anti-inflammatory, analgesic and antipyretic effects. It can inhibit the synthesis of prostaglandins and selectively inhibit cyclooxygenase-2 (COX-2), making it safer than other NSAIDs.

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71125-38-7 57

Appearance

This product is a hard capsule, and the contents are light yellow granules.

Indication

This product is a nonsteroidal anti-inflammatory drug (NSAID) suitable for the treatment of rheumatoid arthritis and painful osteoarthritis (arthrosis, degenerative osteoarthritis).

Usage and Dosage

Rheumatoid arthritis: 15 mg per day, depending on the response after treatment, the dose can be reduced to 7.5 mg/day. Osteoarthritis: 7.5 mg/day, if necessary, the dose can be increased to 15 mg/day. For patients with increased adverse reactions: the initial dose of treatment is 7.5 mg/day. Patients with severe renal failure on dialysis: the dose should not exceed 7.5 mg/day. The dosage for children has not yet been determined, and it is currently limited to adult use. The maximum recommended daily dose is 15 mg, swallowed with water or liquid.

Adverse Reactions

According to foreign research data, the incidence of adverse reactions to oral administration of this product is as follows: 1 Gastrointestinal: Frequency exceeds 1%: indigestion, nausea, vomiting, abdominal pain, constipation, flatulence, diarrhea. Frequency is between 0.1% and 1%: transient abnormal liver function indicators (such as elevated transaminase or bilirubin). Esophagitis, gastric and duodenal ulcers, latent or visible gastrointestinal bleeding. Frequency is less than 0.1%: gastrointestinal perforation, colitis. 2 Blood: Frequency exceeds 1%: anemia. Frequency is between 0.1% and 1%: blood cell count disorders, including white blood cell differential count, leukopenia and thrombocytopenia,

Precautions

It should not be used by patients who are allergic to this product, those with active peptic ulcers, severe liver dysfunction, those with severe renal dysfunction not on dialysis, patients who have symptoms such as asthma, nasal polyps, angioedema or urticaria after using acetylsalicylic acid or other NSAIDs, children and adolescents under 15 years old, and pregnant or lactating women.

Special Population Medication

Precautions for children: The safety of this product in children has not been established, and this product is contraindicated for patients under 15 years of age. Precautions for pregnancy and lactation: Although no teratogenic effects of this product were observed in preclinical trials, this product is contraindicated for pregnant and lactating women. Precautions for the elderly: Elderly patients are more likely to have concomitant kidney, liver or heart diseases, so they should be carefully monitored during medication.

Drug Interactions

1 Large doses of other NSAIDs including salicylates: The simultaneous use of more than one NSAID may increase the likelihood of gastrointestinal ulcers and bleeding through synergistic effects. 2 Oral anticoagulants, ampicillin, systemic use of heparin, and thrombolytics may increase the likelihood of bleeding. If the above combination medications are unavoidable, the effects of anticoagulants must be closely monitored. 3 Lithium: NSAIDs have been reported to increase plasma concentrations of lithium. Therefore, it is recommended to monitor plasma lithium levels when starting, adjusting, and discontinuing this product. 4 Methotrexate: Similar to other NSAIDs, meloxicam can increase the blood toxicity of methotrexate. In this case, it is recommended to strictly monitor blood cell counts. <br/

Storage

Keep in a dark and airtight container, out of the reach of children. The validity period is tentatively set at two years.

Packaging Specification

7.5mg

Validity Period

24 months

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