Cefaclor Tablets
Function and Efficacy
This product is a broad-spectrum semi-synthetic cephalosporin antibiotic. Its activity against penicillinase-producing Staphylococcus aureus, group A hemolytic streptococci, viridans streptococci and Staphylococcus epidermidis is the same as that of cefadroxil, and its antibacterial effect against non-enzyme-producing Staphylococcus aureus and pneumococci is 2 to 4 times stronger than that of cefadroxil. Its activity against Gram-negative bacilli, including Escherichia coli and Klebsiella pneumoniae, is stronger than that of cefadroxil, and is similar to that of cefadroxil. Its activity against Proteus mirabilis, Salmonella and Shigella is stronger than that of cefadroxil. 2.9 to 8 mg/L of this product can inhibit all Haemophilus influenzae, including strains resistant to ampicillin. Moraxella catarrhalis and Neisseria gonorrhoeae are very sensitive to this product. Indole-positive Proteus, Serratia, Acinetobacter and Pseudomonas aeruginosa are all resistant to this product. The mechanism of action of this product is to inhibit the synthesis of bacterial cell walls.
Ingredients
Cefaclor
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| CefaclorIngredients |
This product is a broad-spectrum semi-synthetic cephalosporin antibiotic. Its activity against penicillinase-producing Staphylococcus aureus, group A hemolytic streptococci, viridans streptococci and Staphylococcus epidermidis is the same as that of cefadroxil, and its antibacterial effect against non-enzyme-producing Staphylococcus aureus and pneumococci is 2 to 4 times stronger than that of cefadroxil. Its activity against Gram-negative bacilli, including Escherichia coli and Klebsiella pneumoniae, is stronger than that of cefadroxil, and is similar to that of cefadroxil. Its activity against Proteus mirabilis, Salmonella and Shigella is stronger than that of cefadroxil. 2.9 to 8 mg/L of this product can inhibit all Haemophilus influenzae, including strains resistant to ampicillin. Moraxella catarrhalis and Neisseria gonorrhoeae are very sensitive to this product. Indole-positive Proteus, Serratia, Acinetobacter and Pseudomonas aeruginosa are all resistant to this product. The mechanism of action of this product is to inhibit the synthesis of bacterial cell walls. More |
53994-73-3 | 28 |
Appearance
This product is a film-coated tablet, which appears white to slightly yellowish after removing the coating.
Indication
This product is mainly suitable for respiratory system, urinary system, ENT, skin and soft tissue infections caused by sensitive bacteria.
Usage and Dosage
This product is suitable for oral administration on an empty stomach. The usual dosage for adults is 0.25g (1 tablet) at a time, 3 times a day. In case of severe infection, the dosage can be doubled, but the total amount per day should not exceed 4g (16 tablets), or follow the doctor's advice. Children are generally given 20mg/kg per day according to body weight, divided into 3 times. In severe infection, the dosage can be increased to 40mg/kg, but the total amount per day should not exceed 1g (4 tablets).
Adverse Reactions
1 Nausea, vomiting, diarrhea and abdominal discomfort are more common. 2 Allergic reactions such as rash and drug fever. 3 Nervous system reactions such as dizziness, diplopia, tinnitus, convulsions, etc. 4 Transient renal damage may occur occasionally during the use of this product. 5 Occasionally, patients have elevated serum aminotransferase and positive Coombs test. Hemolytic anemia is rare, and neutropenia and pseudomembranous colitis have also been reported.
Precautions
Patients who are allergic to cefaclor and other cephalosporins are contraindicated.
Special Population Medication
Precautions for children: The safety of the drug for newborns has not yet been determined. Precautions for pregnancy and lactation: 1. Pregnant women should use with caution. 2. This product can be excreted through breast milk, so lactating women should use it with caution or stop breastfeeding. Precautions for the elderly: Elderly patients should adjust the dosage or medication interval according to their renal function under the guidance of a physician.
Drug Interactions
1. Furosemide, ethacrynic acid, bumetanide and other strong diuretics, carmustine, streptozocin and other antineoplastic drugs and aminoglycoside antibiotics and other nephrotoxic drugs combined with this product may increase nephrotoxicity. 2. Clavulanic acid can enhance the antibacterial activity of this product against certain Gram-negative bacteria that are resistant to this product due to the production of beta-lactamase. 3. Oral administration of probenecid can delay the excretion of this product.
Storage
Keep away from light, seal tightly, and store in a cool, dark, and dry place. Validity period: 24 months
Packaging Specification
0.25g
Validity Period
24 months
Manufacturer
Jiangsu Lianshui Pharmaceutical Co., Ltd.
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Founded in:
1999-05-21 -
Address:
No. 18, Hongri Avenue, Lianshui Economic Development Zone -
Tax NO.:
91320826139830519D -
Registered Funds:
80 million yuan -
Email: