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Eprazone Hydrochloride Tablets

Function and Efficacy

Phenylpropion is a non-addictive antitussive drug with both central and peripheral antitussive effects, and mainly acts on the cough center. Animal experiments show that it selectively inhibits the brainstem reticular body, including the cough center of the medulla oblongata, and its intensity is similar to or 1/3 of codeine, 2 times that of dextromethorphan, and 3 times that of narcotine. The clinical antitussive effect of this product is similar to or slightly inferior to that of codeine, but it does not have the intestinal peristalsis inhibitory effect of codeine. This product has both expectorant effects, can change the properties of the polysaccharide fibers of acidic glycoproteins in sputum, and cause the mucopolysaccharide fibers to swell and break, and has a strong mucolytic effect. In addition, experimental results also show that this product also has sedative effects, local anesthetic effects, and antihistamine and anticholinergic effects, and can relieve bronchial smooth muscle spasms caused by histamine, acetylcholine and 5-hydroxytryptamine.

Ingredients

The main ingredient of this product is phenylpropion hydrochloride.

Name Description Content CAS NO. Manufacturer
Eprazinone dihydrochlorideIngredients

A non-addictive antitussive drug with both central and peripheral antitussive effects. It mainly acts on the cough center, selectively inhibiting the corpus reticularis in the brainstem, including the cough center in the medulla oblongata. Its clinical antitussive effect is similar to or slightly inferior to that of codeine, but it does not have the intestinal peristalsis inhibitory effect of codeine. It also has an expectorant effect, which can change the polysaccharide fiber properties of acidic glycoproteins in sputum, causing the mucopolysaccharide fibers to swell and break, and has a strong mucolytic effect. It also has sedative, local anesthetic, antihistamine, and anticholinergic effects, and can relieve bronchial smooth muscle spasms caused by histamine, acetylcholine, and 5-hydroxytryptamine.

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10402-53-6 1

Appearance

This product is a white sugar-coated tablet. The tablet core after removing the sugar coating is white or off-white.

Indication

It is suitable for suppressing cough and removing phlegm for diseases such as acute and chronic bronchitis, asthma, pneumonia, tuberculosis, emphysema, etc.

Usage and Dosage

Oral administration. 40-80 mg (1-2 tablets) at a time, 3-4 times a day. The dose for children is halved.

Adverse Reactions

A small number of patients may experience dizziness, dry mouth, stomach discomfort and nausea.

Precautions

Not clear yet

Special Population Medication

Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Not yet clear. Precautions for the elderly: Not yet clear.

Drug Interactions

Not clear yet

Storage

Sealed storage

Packaging Specification

40mg

Validity Period

36 months

Manufacturer

Shanghai Hengshan Pharmaceutical Co., Ltd.

  • Founded in:

    1981-07-20
  • Address:

    No. 176, Zidong Road, Minhang District, Shanghai
  • Tax NO.:

    91310112132628617W
  • Registered Funds:

    47.46 million yuan
  • Website:

  • Email:

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