Megestrol acetate tablets

This product is a progestin that has a certain inhibitory effect on the release of pituitary gonadotropin, but it is weaker than levonorgestrel and norgestrel. It does not have estrogen and androgen-like activity, but has obvious anti-estrogen effects. When used in combination with estrogen, it inhibits ovulation. Animal teratogenicity tests have shown that it has an increased stillbirth rate and teratogenic effects on rabbits.

The main ingredients of this product and its chemical name: The main ingredient of this product is megestrol acetate. Its chemical name is: 6-methyl-17alpha;-hydroxypregnant-4,6-diene-3,20-dione 17-acetate. Its structural formula is: Molecular formula: C24H32O4 Molecular weight: 384.52.

This product is white or off-white tablets.

It can be used to treat irregular menstruation, functional uterine bleeding, endometriosis, advanced breast cancer and endometrial adenocarcinoma; it can also be used as the progestin component of short-acting combined oral contraceptive tablets.

Oral: 1. Treatment of amenorrhea (when estrogen levels are sufficient), 4 mg once, 2-3 times a day, for 2-3 consecutive days, withdrawal bleeding will occur within 2 weeks of stopping the drug; 2. Treatment of functional uterine bleeding, 4 mg-8 mg a day, for 20 days, starting from the 5th day of menstruation or the same as 1); 3. Treatment of endometriosis, 4 mg-8 mg once, 1A-2 times a day, starting from the 5th day of menstruation, for 3-6 months; 4. Breast cancer, 40 mg once, 4 times a day, 160 mg a day, for 2 consecutive months; 5. Endometrial cancer, 10-80 mg once, 4 times a day, 40-320 mg a day, or 160 mg once a day.

1 Mainly nausea, dizziness, and fatigue; 2 Breakthrough bleeding; 3 Taking it during pregnancy has a relatively clear effect of increasing the masculinization of female offspring.

It is contraindicated for patients with severe liver and kidney dysfunction, breast tumors, and pregnant women.

Precautions for children: The safety and effectiveness for children have not been proven. Precautions for pregnancy and lactation: 1. Since the use of progesterone drugs in the first four months of pregnancy has potential harm to the fetus, this product should not be used in the first four months of pregnancy. 2. This product has potential toxic effects on newborns, and breastfeeding women should stop breastfeeding during the medication period. Precautions for the elderly: This experiment has not been conducted and there is no reliable reference literature.

Not yet clear.

Keep away from light and store in sealed container.

160mg

24 months

Shanghai Sine Tianping Pharmaceutical Co., Ltd.

• Founded in:

  1998-05-07

• Address:

  No. 4598, Jindu Road, Minhang District, Shanghai

• Tax NO.:

  91310112832231856K

• Registered Funds:

  154.7 million yuan

• Email:

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