Aminophylline Tablets

The main ingredient of this product is: aminophylline.

This product is white or slightly yellow tablets.

1. The usual oral dose for adults is 0.1-0.2g at a time, 0.3-0.6g per day; the maximum dose is 0.5g at a time, 1g per day. 2. The usual oral dose for children is 3-5mg/kg per time, 3 times a day.

The toxicity of theophylline often occurs at a serum concentration of 15-20μg/ml, especially at the beginning of treatment. Common symptoms in the early stage include nausea, vomiting, irritability, insomnia, etc. When the serum concentration exceeds 20μg/ml, tachycardia and arrhythmia may occur. When the theophylline in the serum exceeds 40μg/ml, symptoms such as fever, dehydration, and convulsions may occur. In severe cases, respiratory and cardiac arrest may occur, leading to death.

It is contraindicated for patients who are allergic to this product, those with active peptic ulcers and uncontrolled convulsive diseases.

Precautions for children: The plasma clearance rate of newborns may be reduced and the serum concentration may increase, so it should be used with caution. Precautions for pregnancy and lactation: This product can pass through the placental barrier and can also be secreted into breast milk and excreted with breast milk. It should be used with caution by pregnant women, parturients and lactating women. Precautions for the elderly: The plasma clearance rate of the elderly is reduced and the potential toxicity is increased. It should be used with caution in patients over 55 years old.

⑴ Diltiazem and verapamil can interfere with the metabolism of theophylline in the liver. When used in combination with this product, the blood concentration and toxicity of this product can be increased. ⑵ Cimetidine can reduce the liver clearance rate of this product. When used in combination, it can increase the serum concentration and (or) toxicity of theophylline. ⑶ Certain antibacterial drugs, such as erythromycin, roxithromycin, and clarithromycin of the macrolide class, and enoxacin, ciprofloxacin, ofloxacin, levofloxacin, clindamycin, and lincomycin of the fluoroquinolone class, can reduce the clearance rate of theophylline and increase its blood concentration, especially erythromycin and enoxacin. When theophylline is used in combination with the above drugs, the dosage should be appropriately reduced. ⑷ Phenobarbital, phenytoin, and rifampicin can induce liver enzymes and accelerate the liver clearance rate of theophylline; theophylline also interferes with the absorption of phenytoin. The plasma concentrations of both decrease, and the dosage should be adjusted when used in combination. ⑸ With lithium salts

Keep away from light and store in sealed container.

0.1g*100s

24 months

Puyang Huiyuan Pharmaceutical Co., Ltd.

• Founded in:

  2004-03-04

• Address:

  At the southwest corner of the intersection of Tieqiu Road and Panjin Road, Puyang County

• Tax NO.:

  91410900758391375Q

• Registered Funds:

  70 million yuan

• Website:

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• Email:

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