Actarit tablets
Function and Efficacy
The mechanism of action of this product is still unclear, but it may be related to the inhibition of the production of IL-1?, IL-6, TNF-??? and MMP-1 in the synovial cells of the patient's joint cavity. The results of animal experiments suggest that this product has a control effect on the development of arthritis lesions in rheumatoid arthritis-related model animals (type II collagen arthritis mice, spontaneous autoimmune arthritis NRL/Ipr mice), and this product has an improvement effect on the condition of patients with rheumatoid arthritis, but has no analgesic and anti-inflammatory effects.
Ingredients
Chemical name: 4-acetylaminophenylacetic acid Molecular weight: C10H11N03193.20
Appearance
This product is white or off-white tablets.
Indication
Rheumatoid arthritis.
Usage and Dosage
Oral administration with other anti-inflammatory analgesics, 0.1 g (1 tablet) at a time, 3 times a day
Adverse Reactions
According to Japanese literature reports: 1. Serious adverse reactions: (1) Nephrotic syndrome: Nephrotic syndrome has occurred before (the incidence is unknown), so you should pay close attention to regular inspections and monitoring. Once abnormalities occur, the drug should be discontinued and appropriate measures should be taken. (2) Interstitial pneumonia: Interstitial pneumonia accompanied by fever, cough, dyspnea, and chest X-ray abnormalities has occurred before (less than 0.1%), so pay attention to observe the patient's symptoms. Once the above symptoms occur, the drug should be discontinued, and treatment such as adrenal cortex hormones should be given and appropriate measures should be taken. 2. Other adverse reactions (1) Kidney: Abnormal renal function (increased proteinuria, BUN, creatinine, and NAG in urine), hematuria. (2) Liver: Abnormal liver function (increased GOT, GPT, AL-P, etc.). (3) Blood:
Precautions
Not yet clear.
Special Population Medication
Precautions for children: Forbidden. Precautions for pregnancy and lactation: Forbidden. Precautions for the elderly: This product is mainly excreted through the kidneys, and elderly patients often have low renal function, so they may continue to have high blood drug concentrations. Therefore, elderly patients should start with a low dose, such as 1 tablet at a time, twice a day. In addition, regular clinical observations should be conducted, and the drug should be discontinued if abnormalities are found.
Drug Interactions
Drug interactions may occur if used with other drugs. Please consult your doctor or pharmacist for details.
Storage
seal.
Packaging Specification
0.1g
Validity Period
24 months
Manufacturer
Suzhong Pharmaceutical Group Co., Ltd.
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Founded in:
1979-11-26 -
Address:
No. 1 Suzhong Road, Taizhou City, Jiangsu Province -
Tax NO.:
91321200141355745E -
Registered Funds:
160 million yuan -
Website:
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Email: