Idarubicin Hydrochloride for Injection

This drug is an anthracycline antibiotic with antimitotic and cytotoxic effects. This drug is an anthracycline antibiotic with antimitotic and cytotoxic effects. Its mechanism of action is to act on topoisomerase II and inhibit nucleic acid synthesis. The change in the 4-position of the anthracene ring structure makes the compound lipophilic, which increases the cell's uptake of the drug.

Keep tightly closed in a dry place.

This product is an orange-red loose freeze-dried block, which is hygroscopic.

Intravenous injection has a good effect on acute non-lymphocytic leukemia and acute lymphocytic leukemia. Oral administration has a certain relieving effect on non-Hodgkin's disease, advanced breast cancer, and multiple myeloma.

Adults with acute non-lymphocytic leukemia take 12 mg/m2/day for 3 days, combined with cytarabine; another method is to use it alone or in combination: 8 mg/m2/day, intravenous injection, for 5 days. Adults with acute lymphocytic leukemia take 12 mg/m2/day for 3 days. Children take 10 mg/m2/day for 3 days. Intravenous injection. Based on the recommended dose, the amount after 2 courses of medication can reach 60-80 mg/m2. Although there is no upper limit, the average dose to avoid cardiac events in cancer patients is 93 mg/m2.

Severe bone marrow suppression and cardiotoxicity, fatal infections. Reversible alopecia, gastrointestinal reactions such as nausea, vomiting, mucositis, especially oral mucositis, which occurs 3-10 days after treatment, esophagitis, diarrhea, fever, chills, rash. There are enzymes and bilirubin increase. Urine turns red after 1-2 days of using this drug.

Severe punishment for liver and kidney dysfunction, uncontrolled infection, heart disease patients who have received drug or radiation therapy that caused bone marrow suppression

Combination with other drugs that have bone marrow suppression may aggravate bone marrow suppression. It will degrade with alkaline solution. Combination with heparin will produce precipitation, so do not use with other drugs.

Keep tightly closed in a dry place.

10mg

Pfizer Pharmaceutical Wuxi Co., Ltd.

• Founded in:

  1995-09-19

• Address:

  No. 7 Mashan Bridge, Binhu District, Wuxi City

• Tax NO.:

  913202006079219223

• Registered Funds:

  $36 million

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