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Compound Glycyrrhizin Tablets

Function and Efficacy

1. Anti-allergic effect: Glycyrrhizic acid glycoside can inhibit the local allergic reaction of rabbits (Arthus Phenomenon) and inhibit the anti-allergic effect of Schwartsman Phenomenon. For corticosteroids, it can enhance the hormone's inhibitory effect on stress response and antagonize the hormone's anti-granulation and thymus atrophy effect. It has no effect on the exudation of hormones. 2. Inhibition of arachidonic acid metabolic enzymes: Glycyrrhizic acid glycoside can directly bind to phospholipase A2, the starting enzyme of the arachidonic acid metabolic pathway, and act on arachidonic acid to produce inflammatory mediators. See the inner package insert for details.

Ingredients

Each tablet of the MeiNeng compound preparation contains 25 mg of glycyrrhizin, 35 mg of monoammonium glycyrrhizinate, 25 mg of glycine, and 25 mg of methionine.

Name Description Content CAS NO. Manufacturer
Glycyrrhizic acidIngredients

Anti-allergic effect: It can inhibit the local allergic reaction of rabbits (Arthus Phenomenon) and inhibit the anti-allergic effect of Schwartsman Phenomenon. It has an inhibitory effect on arachidonic acid metabolic enzymes: It can directly bind to phospholipase A2, the starting enzyme of the arachidonic acid metabolic pathway, and act on arachidonic acid to produce inflammatory mediators.

More
1405-86-3 1
Ammonium GlycyrrhizinateIngredients

1. Anti-allergic effect: Glycyrrhizic acid glycoside can inhibit the local allergic reaction of rabbits (Arthus Phenomenon) and inhibit the anti-allergic effect of Schwartsman Phenomenon. For corticosteroids, it can enhance the hormone's inhibitory effect on stress response and antagonize the hormone's anti-granulation and thymus atrophy effect. It has no effect on the exudation of hormones. 2. Inhibition of arachidonic acid metabolic enzymes: Glycyrrhizic acid glycoside can directly bind to phospholipase A2, the starting enzyme of the arachidonic acid metabolic pathway, and act on arachidonic acid to produce inflammatory mediators. See the inner package insert for details.

More
1407-03-0 1
GlycineIngredients

1. Anti-allergic effect: Glycyrrhizic acid glycoside can inhibit the local allergic reaction of rabbits (Arthus Phenomenon) and inhibit the anti-allergic effect of Schwartsman Phenomenon. For corticosteroids, it can enhance the hormone's inhibitory effect on stress response and antagonize the hormone's anti-granulation and thymus atrophy effect. It has no effect on the exudation of hormones. 2. Inhibition of arachidonic acid metabolic enzymes: Glycyrrhizic acid glycoside can directly bind to phospholipase A2, the starting enzyme of the arachidonic acid metabolic pathway, and act on arachidonic acid to produce inflammatory mediators. See the inner package insert for details.

More
56-40-6 27
L-MethionineIngredients

1. Anti-allergic effect: Glycyrrhizic acid glycoside can inhibit the local allergic reaction of rabbits (Arthus Phenomenon) and inhibit the anti-allergic effect of Schwartsman Phenomenon. For corticosteroids, it can enhance the hormone's inhibitory effect on stress response and antagonize the hormone's anti-granulation and thymus atrophy effect. It has no effect on the exudation of hormones. 2. Inhibition of arachidonic acid metabolic enzymes: Glycyrrhizic acid glycoside can directly bind to phospholipase A2, the starting enzyme of the arachidonic acid metabolic pathway, and act on arachidonic acid to produce inflammatory mediators. See the inner package insert for details.

More
63-68-3 12

Appearance

This product is a white sugar-coated tablet.

Indication

Treat chronic liver disease and improve abnormal liver function. Can be used to treat eczema, dermatitis and alopecia areata.

Usage and Dosage

Adults usually take 2-3 tablets at a time, and children take 1 tablet at a time, 3 times a day after meals. The dosage can be increased or decreased according to age and symptoms.

Adverse Reactions

The actual frequency of adverse reactions in the use of this preparation has not been investigated. Important adverse reactions: Pseudoaldosteronism (frequency unknown): Symptoms of pseudoaldosteronism such as hypokalemia, increased blood pressure, sodium and fluid retention, edema, decreased urine volume, and weight gain may occur. Therefore, during medication, it is necessary to observe carefully (serum potassium value, etc.), and if abnormal conditions are found, the medication should be stopped. In addition, symptoms of rhabdomyolysis such as weakness, low muscle strength, muscle pain, limb cramps, and paralysis may also occur. If CK (CPK) is found to be elevated, and myoglobin in blood and urine is elevated, the medication should be stopped and appropriate treatment should be given.

Precautions

The following patients should not be given the drug: 1. Patients with aldosteronism, myopathy, and hypokalemia (which may aggravate hypokalemia and hypertension). 2. Patients with advanced liver cirrhosis who tend to have elevated blood ammonia (the methionine metabolites contained in this preparation can inhibit urea synthesis, thereby reducing the ability to handle ammonia).

Special Population Medication

Precautions for children: There are no studies on pharmacology, toxicology or pharmacokinetics that differ from those for adults. For drug use, please refer to [Usage and Dosage] and [Precautions]. Precautions for pregnancy and lactation: Pregnant and lactating women should be given the drug with caution after weighing the benefits of treatment outweigh the risks. Precautions for the elderly: Based on clinical application experience, the elderly are prone to hypokalemia side effects, so they need to be given with caution under close observation.

Drug Interactions

If used with other drugs at the same time, drug interactions may occur. Please consult your doctor or pharmacist for details. See the inner package insert for details.

Storage

Store at room temperature (1-30℃).

Packaging Specification

25mg*10s*10 plates

Validity Period

60 months.

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