Dextran 70 Glucose Injection

This product is a blood volume expander. After intravenous injection, it can increase plasma colloidal osmotic pressure, absorb extravascular water to increase blood volume, and increase and maintain blood pressure. The increase in plasma volume is related to the amount of dextran input. However, its blood volume expansion effect is stronger than dextran 40, and it has almost no effect on improving microcirculation and osmotic diuresis. In addition, this product can also reduce the activity of certain coagulation factors and platelets, and thus has a certain anti-thrombotic effect. This product has strong antigenicity. Since there are bacteria that produce this product in the normal intestine, some patients will have allergic reactions even after the first injection of this product. Mainly skin and mucous membrane allergic reactions.

Main ingredients: This product is a sterile aqueous solution of dextran 70 and glucose. Dextran 70 is a high molecular weight glucose polymer generated by fermentation of sucrose, with an average molecular weight of 70,000.

1. Shock Prevention and treatment of various hypovolemic shocks such as hemorrhagic shock, intraoperative shock, burn shock, etc. 2. Prevention of postoperative venous thrombosis and thrombophlebitis.

Intravenous drip, the dosage depends on the condition. The common dose is 500ml each time. In shock, the dose for rapid volume expansion is usually 500-1000ml, 20-40ml per minute, and the maximum recommended dose on the first day is 20ml/kg. To prevent postoperative venous embolism, 500ml can be given during or after surgery, and 500ml can be continued on the second day. For high-risk patients, the course of treatment can be up to 10 days.

1. Allergic reaction: A small number of patients may experience allergic reactions, manifested as skin itching, urticaria, nausea, vomiting, asthma, cyanosis of the lips, collapse, a sharp drop in blood pressure, bronchospasm in severe cases, and some patients may even experience anaphylactic shock and even death. The incidence of allergic reactions is about 0.03-4.7%. 2. Occasionally, fever, chills, swollen lymph nodes, arthritis, etc. 3. Bleeding tendency: It can cause coagulation disorders and prolong bleeding time. This reaction is often related to the dose. 4. Red blood cell aggregation: As the molecular weight of dextran increases, red blood cell aggregation is more and more obvious.

1. Contraindicated for patients with congestive heart failure and other hypervolemia. 2. Contraindicated for patients with severe thrombocytopenia, coagulation disorders and other bleeding conditions. 3. Use with caution in patients with poor heart, liver and kidney function; contraindicated for patients with oliguria or anuria. 4. Use with caution in patients with active pulmonary tuberculosis. 5. Use with caution in patients with a history of allergies. Contraindicated for patients with oliguria or anuria.

1. When used in combination with heparin, the possibility of bleeding increases due to synergistic effects. 2. When used in combination with gentamicin and paromomycin, nephrotoxicity increases.

Store below 25°C.

500ml: 30g of Dextran 70 and 25g of glucose

Echo Group Jiangxi Dongya Pharmaceutical Co., Ltd.

• Founded in:

  2005-08-10

• Address:

  No. 6 Huiyingbi Road, Dongshan Industrial Park, Economic Development Zone, Dongxiang District, Fuzhou City, Jiangxi Province

• Tax NO.:

  91361029778807964A

• Registered Funds:

  73.333333 million yuan

• Email:

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