Famotidine Sodium Chloride Injection
Function and Efficacy
This product is a H2 receptor blocker of the guanyl thiazole class, which has the characteristics of high affinity for H2 receptors, and has a significant inhibitory effect on gastric acid secretion, and has an inhibitory effect on basal secretion and the increase of gastric acid and pepsin caused by various stimuli. This product does not change the gastric emptying rate, does not interfere with pancreatic function, and has no adverse effects on the cardiovascular system and kidney function. This product is different from cimetidine, but it is similar to ranitidine, that is, long-term high-dose treatment does not cause adverse reactions of androgen antagonism such as male breast development, impotence, lack of sexual desire, and female breast pain, galactorrhea, etc. It has no teratogenic, carcinogenic, drug enzyme inhibitory and androgen inhibitory effects.
Ingredients
The main ingredient of this product is famotidine. Its chemical name is 3-[[[2-[(diaminomethylene)amino]-4-thiazolyl]methyl]thio]-N-sulfamoylpropionamidine. Molecular formula: C8H15N7O2S3, molecular weight: 337.45.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| FamotidineIngredients |
This product is a H2 receptor blocker of the guanyl thiazole class, which has the characteristics of high affinity for H2 receptors, and has a significant inhibitory effect on gastric acid secretion, and has an inhibitory effect on basal secretion and the increase of gastric acid and pepsin caused by various stimuli. This product does not change the gastric emptying rate, does not interfere with pancreatic function, and has no adverse effects on the cardiovascular system and kidney function. It is different from cimetidine, but similar to ranitidine, that is, long-term high-dose treatment does not cause adverse reactions of androgen antagonism such as male breast development, impotence, lack of sexual desire, and female breast pain and galactorrhea. It has no teratogenic, carcinogenic, drug enzyme inhibitory and androgen inhibitory effects. More |
76824-35-6 | 69 |
Appearance
This product is a colorless clear liquid.
Indication
Upper gastrointestinal bleeding caused by peptic ulcer, and bleeding from gastric and duodenal mucosal erosion caused by various reasons other than tumors and esophageal and gastric fundus varices.
Usage and Dosage
In patients with peptic ulcer complicated by upper gastrointestinal bleeding or gastric and duodenal mucosal erosion and bleeding, when gastric acid secretion must be reduced and oral administration is not suitable, use 20 mg of this product by intravenous drip for more than 30 minutes, twice a day (12 hours apart), for a course of 5 days. Once the condition permits, intravenous administration should be quickly changed to oral administration.
Adverse Reactions
1 Irritation: Irritation rarely occurs. Observe thoroughly. When abnormality occurs, stop taking the drug and take appropriate measures. 2 Allergic reaction: Facial edema, rash, rashes, urticaria, (erythema) may occur rarely. When these symptoms occur, stop taking the drug. 3 Blood: Rare symptoms of thrombocytopenia or leukopenia. When abnormality is found, stop taking the drug. 4 Digestive system: Constipation, soft stools, thirst, nausea, vomiting, abdominal distension, loss of appetite and transient changes in liver function are occasionally seen. 5 Circulatory system: Increased blood pressure, facial flushing, tinnitus, etc. are occasionally seen. 6 General fatigue,
Precautions
It is contraindicated for people who are allergic to this product, those with severe renal insufficiency, and pregnant or lactating women.
Special Population Medication
Precautions during pregnancy and lactation: Pregnant and lactating women are prohibited from using
Drug Interactions
It has been reported that this product has a mild effect on the pharmacokinetics of theophylline, warfarin, diazepam and nifedipine; probenecid inhibits the excretion of famotidine from the renal tubules.
Storage
Keep in a dark, airtight, cool place. The validity period is tentatively set at two years.
Packaging Specification
100ml: 0.02g famotidine and 0.9g sodium chloride
Manufacturer
Echo Group Jiangxi Dongya Pharmaceutical Co., Ltd.
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Founded in:
2005-08-10 -
Address:
No. 6 Huiyingbi Road, Dongshan Industrial Park, Economic Development Zone, Dongxiang District, Fuzhou City, Jiangxi Province -
Tax NO.:
91361029778807964A -
Registered Funds:
73.333333 million yuan -
Email: