Mirtazapine Tablets

Mirtazapine is an antidepressant. It acts as a presynaptic a2 receptor antagonist in the central nervous system and can enhance adrenergic nerve conduction. It regulates the function of 5-hydroxytryptamine by interacting with the central 5-hydroxytryptamine receptors (5-HT2 and 5-HT3). Both optical enantiomers of mirtazapine have antidepressant activity, the left-handed enantiomer blocks a2 and 5-HT2 receptors, and the right-handed enantiomer blocks 5-HT3 receptors. The antihistamine receptor (H1) property of mirtazapine plays a sedative role. The drug has good tolerance, almost no anticholinergic effect, and its therapeutic dose has no effect on the cardiovascular system.

Mirtazapine.

It is an oval, reddish brown film-coated tablet with raised sides. One side has the word "Organon" and the other side has the code. The tablet is scored.

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The tablets are taken orally, with water if necessary, and should be swallowed rather than chewed. Adults: The effective dose is usually 15-45 mg per day. The initial dose of treatment should be 15 or 30 mg (a higher dose should be taken at night). Patients with impaired liver and kidney function may have reduced clearance of miclopine, and such patients should be careful when using Remeron. The half-life of miclopine, the active ingredient in Remeron, is 20 to 40 hours, so the drug is suitable for once-daily administration (preferably before bedtime). The drug can also be taken in divided doses (such as once in the morning and once in the evening). Patients should take the drug continuously, preferably gradually stopping it four to six months after the symptoms have completely disappeared. When the dose is appropriate, the drug should have a significant therapeutic effect within two to four weeks. If the effect is not significant enough, the dose can be increased for two to four weeks, but if there is still no effect, the drug should be discontinued.

Since patients with depression often show symptoms caused by the disease itself, it is not possible to distinguish which side effects are caused by the use of this drug. The following are the most common side effects during the use of this drug: increased appetite, weight gain. Drowsiness and sedation usually occur in the first few weeks after taking the drug (reducing the dose at this time will not reduce the side effects, but will affect its antidepressant effect). In rare cases, the following side effects may occur: postural hypotension, mania, convulsions, tremors, muscle spasms, edema and weight gain, increased serum transaminase levels, and drug rash.

Patients who are allergic to milclopine are contraindicated.

Precautions for children: Children: Since the effectiveness and safety of this drug for children have not been confirmed, it is not recommended for children to use this drug. Precautions for pregnancy and lactation: There are not enough clinical trial results to evaluate the effect of Remeron on pregnancy. In animal experiments, this drug has no teratogenic side effects on the embryo. Although only a small amount of drug ingredients can be secreted from the milk of animals, due to the lack of clinical trial data, it is not recommended for lactating patients to take this drug. Precautions for the elderly: The elderly: The dosage is the same as that for adults, and the dosage should be gradually increased under the close observation of a doctor in order to achieve a satisfactory therapeutic effect.

Mirtazapine can increase the inhibitory effect of alcohol, so patients should refrain from drinking alcohol during treatment. Patients who are currently using monoamine oxidase inhibitors or have stopped taking them within 2 weeks should not use this drug. Mirtazapine may increase the drowsiness of benzodiazepines, so caution should be exercised when used in combination.

Keep away from light and store in sealed container.

30mg

36 months