Azelnidipine

Azelnidipine is a new type of dihydropyridine calcium channel blocker. It has characteristics that general calcium antagonists do not have. It can slow down the heart rate and has a high affinity with vascular tissue. Because of its mild action, it rarely causes reflex tachycardia. Although the antihypertensive response-time curve of azelnidipine after a single oral dose is very similar to that of the third-generation calcium antagonist amlodipine, the tachycardia caused by taking azelnidipine is less than that of amlodipine. After long-term use of azelnidipine, the heart rate and PRA tend to decrease compared with the control group. Due to its high lipid solubility, it is mainly distributed in vascular tissue. Therefore, in many animal models, azelnidipine also shows good anti-atherosclerotic and kidney and heart protective effects. Therefore, azelnidipine can also be used to treat atherosclerosis.

C33H34N4O6

Anti-hypertensive.

API

Lianyungang Runzhong Pharmaceutical Co., Ltd.

• Founded in:

  2010-10-20

• Address:

  No. 16, Jinqiao Road, Dapu Industrial Zone, Lianyungang Economic and Technological Development Zone

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  913207005629851634

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