Granisetron Hydrochloride Orally Disintegrating Tablets

This product is a highly selective 5-HT3 receptor antagonist, which has a good preventive and therapeutic effect on nausea and vomiting caused by radiotherapy, chemotherapy and surgery. Factors such as radiotherapy, chemotherapy and surgery can cause enterochromaffin cells to release 5-HT, which can activate the 5-HT3 receptors of the central nervous system or vagus nerve and cause vomiting reflex. The mechanism of this product in controlling nausea and vomiting is to antagonize the 5-HT3 receptors in the central chemoreceptor area and peripheral vagus nerve endings, thereby inhibiting the occurrence of nausea and vomiting. This product has high selectivity and no side effects such as extrapyramidal reactions and excessive sedation.

The main ingredient of this product is granisetron hydrochloride.

This product is a white or off-white tablet that disintegrates quickly in the mouth, has no gritty feeling, and has a good taste.

Used to prevent and treat nausea and vomiting caused by radiotherapy and cytotoxic chemotherapy.

Usage: Take the double aluminum plate out of the foam splint, cut the double aluminum plate into a 90-degree angle with scissors, take out the tablet gently with dry hands, and place it on the tongue for a few seconds to disintegrate or dissolve. The disintegrated product can then be swallowed without water. Do not tear the tablet vigorously during the tablet removal process to prevent the tablet from breaking. Dosage: The usual adult dosage is 1 mg/time, 2 times/day. The first dose is taken 1 hour before chemotherapy and radiotherapy, and the second dose is taken 12 hours after the first dose. The elderly and patients with liver and kidney dysfunction do not need to adjust the dose. Maximum daily dose: no more than 9 mg within 24 hours.

Usage: Take the double aluminum plate out of the foam splint, cut the double aluminum plate into a 90-degree angle with scissors, take out the tablet gently with dry hands, and place it on the tongue for a few seconds to disintegrate or dissolve. The disintegrated product can then be swallowed without water. Do not tear the tablet vigorously during the tablet removal process to prevent the tablet from breaking. Dosage: The usual adult dosage is 1 mg/time, 2 times/day. The first dose is taken 1 hour before chemotherapy and radiotherapy, and the second dose is taken 12 hours after the first dose. The elderly and patients with liver and kidney dysfunction do not need to adjust the dose. Maximum daily dose: no more than 9 mg within 24 hours.

1. Patients who are allergic to this product or other 5-HT3 receptor antagonists are contraindicated. 2. Patients with gastrointestinal obstruction are contraindicated.

Precautions for children: There is no experience with the drug in children, so it is not recommended. Precautions for pregnancy and lactation: It is not clear. Precautions for the elderly: No dosage adjustment is required for the elderly.

When used simultaneously with rifampicin or other liver enzyme inducing drugs, the blood concentration of this product will be reduced and the dosage should be appropriately increased.

Keep away from light and sealed. Valid for 18 months.

1mg (as granisetron)

24 months

Fujian Dawnrays Pharmaceutical Co., Ltd.

• Founded in:

  2000-10-10

• Address:

  No. 1399, Lihan West Avenue, Xitianwei Town, Licheng District, Putian City, Fujian Province

• Tax NO.:

  913503006339063551

• Registered Funds:

  98.6948063 yuan

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