Biphenyl double fat tablets

This product is an intermediate in the synthesis of Schisandra chinensis C. Oral administration of 150-200 mg/kg of this product to mice can reduce liver damage and elevated alanine aminotransferase (ALT) caused by carbon tetrachloride. It has an inhibitory effect on liver microsomal lipid peroxidation caused by carbon tetrachloride and the metabolic conversion of carbon tetrachloride into carbon monoxide, and reduces the consumption of reduced coenzyme II and oxygen in the metabolic process of carbon tetrachloride, thereby protecting the structure and function of the hepatocyte biomembrane. This product can also reduce the elevation of liver ALT induced by prednisone and promote liver regeneration in mice with partial hepatectomy. The enzyme-lowering effect of this product does not directly inhibit the activity of serum and liver ALT, nor does it accelerate the inactivation of ALT in the blood, which may be a reflection of the reduction of liver tissue damage. This product has a significant induction effect on the activity of cytochrome P450 enzymes, thereby enhancing the detoxification ability of carbon tetrachloride and certain carcinogens. It has an effect on improving protein metabolism in some hepatitis patients, increasing albumin and reducing globulin. It has no negative conversion effect on HbsAg and HbeAg, and cannot shrink the enlarged liver and spleen.

Chemical name: 4,4-dimethoxy-5,6,5',6'-bis(methylenedioxy)biphenyl-2,2'-dicarboxylic acid dimethyl ester Molecular weight: C20H18O10

Bifendate is a white crystalline powder and is in the form of tablets.

It is used for patients with chronic persistent hepatitis accompanied by abnormally elevated alanine aminotransferase (ALT); it can also be used for elevated ALT caused by chemical drugs.

Oral administration: 25 mg each time, 75 to 150 mg per day, usually 3 times a day.

In some cases, mild nausea and occasional rash may occur after taking the drug.

1. It is contraindicated for those who are allergic to this product. 2. It is contraindicated for those with liver cirrhosis, and should be used with caution for those with chronic active hepatitis. 3. It is contraindicated for pregnant and lactating women.

Precautions for children: Reduce the dosage for children. Precautions for pregnancy and lactation: Pregnant and lactating women are prohibited. Precautions for the elderly: Elderly patients should use this product with caution.

The combined use of inosine can reduce the enzyme-lowering rebound phenomenon of this product.

Keep sealed.

25mg

24 months

Shanxi Weinan Huaren Pharmaceutical Co., Ltd.

• Founded in:

  1998-06-30

• Address:

  No. 13, Weihua Road, Linwei District, Weinan City, Shaanxi Province

• Tax NO.:

  91610502295258593K

• Registered Funds:

  80 million yuan

• Email:

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