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Acetaminophen chewable tablets

Function and Efficacy

This product is an acetanilide antipyretic analgesic. It inhibits cyclooxygenase and selectively inhibits the synthesis of prostaglandins in the hypothalamic temperature regulation center, leading to peripheral vasodilation and sweating to achieve an antipyretic effect. Its antipyretic effect is similar to that of aspirin. It inhibits the synthesis and release of prostaglandins, etc., increases the pain threshold and has an analgesic effect. It is a peripheral analgesic, weaker than aspirin, and is only effective for mild and moderate pain. This product has no obvious anti-inflammatory effect.

Ingredients

The main ingredient of this product is acetaminophen. Its chemical name is N-(4-hydroxyphenyl)acetamide. Molecular formula: C8H9NO2 Molecular weight: 151.16.

Name Description Content CAS NO. Manufacturer
AcetaminophenIngredients

This product is an acetanilide antipyretic analgesic. It inhibits cyclooxygenase and selectively inhibits the synthesis of prostaglandins in the hypothalamic temperature regulation center, leading to peripheral vasodilation and sweating to achieve an antipyretic effect. Its antipyretic effect is similar to that of aspirin. It inhibits the synthesis and release of prostaglandins, etc., increases the pain threshold and has an analgesic effect. It is a peripheral analgesic, weaker than aspirin, and is only effective for mild and moderate pain. This product has no obvious anti-inflammatory effect.

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Appearance

This product is a colored tablet with a sweet taste and fruity aroma.

Indication

It is used to treat fever caused by the common cold or influenza in children, and is also used to relieve moderate pain such as headache, joint pain, migraine, toothache, muscle pain, neuralgia, and dysmenorrhea.

Usage and Dosage

Oral administration: 0.3-0.6g for adults at a time, 0.6-1.8g per day, daily dose should not exceed 2g. Antipyretic treatment generally does not exceed 3 days, analgesic administration should not exceed 10 days. Children should take 10-15mg/kg at a time according to body weight, 3-4 times a day; children under 12 years old should not take more than 5 doses every 24 hours, and the course of treatment should not exceed 5 days.

Adverse Reactions

At conventional doses, acetaminophen has few adverse reactions, and may occasionally cause nausea, vomiting, sweating, abdominal pain, pale skin, etc. In a few cases, allergic dermatitis (rash, skin itching, etc.), granulocytopenia, thrombocytopenia, methemoglobinemia, anemia, liver and kidney damage, etc. may occur. It rarely causes gastrointestinal bleeding.

Precautions

It is contraindicated for patients with severe hepatic and renal impairment and those who are allergic to this product.

Special Population Medication

Precautions for children: Not yet clear. Precautions for pregnancy and lactation: Not yet clear. Precautions for the elderly: Not yet clear.

Drug Interactions

(1) Long-term drinking or use of other liver enzyme inducers, especially barbiturates or anticonvulsants, are more likely to cause liver toxicity when taking this product for a long time or in large quantities. (2) When this product is used in combination with chloramphenicol, it can prolong the half-life of the latter and enhance its toxicity. (3) When used in combination with anticoagulants, it can enhance the anticoagulant effect, so the dosage of anticoagulants should be adjusted. (4) When used in combination with aspirin or other non-steroidal anti-inflammatory drugs for a long time and in large quantities, there is a significant increase in the risk of renal toxicity. (5) When this product is used in combination with the antiviral drug zidovudine, its toxicity can be increased, so simultaneous use should be avoided.

Storage

Seal tightly and store in a cool place.

Packaging Specification

80mg

Validity Period

24 months

Manufacturer

Harbin Xinnongda Food Co., Ltd.

  • Founded in:

    1999-01-19
  • Address:

    No. 9, Taihu North Road, High-tech Industrial Development Zone, Harbin, Heilongjiang Province
  • Tax NO.:

    912301997120372581
  • Registered Funds:

    88.65 million yuan
  • Email:

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