Midecamycin Tablets

This product is a macrolide antibiotic produced by Streptomyces mycarofaciens. It works by acting on the 50S subunit of bacterial ribosomes, inhibiting the synthesis of bacterial proteins, and is a growth-stage antibacterial drug. Its antibacterial properties are similar to those of erythromycin, and it shows strong antibacterial effects on Gram-positive bacteria and mycoplasmas, and also has antibacterial effects on some Gram-negative bacteria such as Neisseria meningitidis and Neisseria gonorrhoeae.

The main ingredient of this product is midecamycin. Its chemical name is [4R-(4R*,5S*,6S*,7R*,9R*,10R*,11E,13E,16R*)]-6-{[3,6-dideoxy-4-O-(2,6-dideoxy-3-carbon-methyl-a-L-ribose-hexopyranosyl)-3-(dimethylamino)-b-D-pyranoglucopyranosyl]oxy}-4,10-dihydroxy-5-methoxy-9,16-dimethyl-2-oxohexaane-11,13-diene-7-acetaldehyde 3,4-b-dipropionate.

This product is a film-coated tablet, which appears white or off-white after removing the coating.

It is mainly suitable for respiratory tract infections and skin, soft tissue and bile tract infections caused by Staphylococcus aureus, hemolytic Streptococcus, Pneumococcus, etc., and can also be used for Mycoplasma pneumonia.

Oral administration: 0.8-1.2g per day for adults, 30-40mg/kg per day for children according to body weight. Take in 3-4 doses.

Gastrointestinal symptoms such as nausea, vomiting, upper abdominal discomfort, loss of appetite, etc. are occasionally seen. Transient increase in serum alanine aminotransferase is occasionally seen. Rash, urticaria and other symptoms are occasionally seen.

Patients who are allergic to this product and macrolide drugs are contraindicated.

Precautions for children: Not clear yet. Precautions for pregnancy and lactation: Animal reproductive This product can cross the placenta, but there is no sign of damage to the fetus. There is no data on the secretion of this product in breast milk. The safety of use in pregnant and lactating women has not been confirmed so far, so this product should be used only when there is no appropriate choice for pregnant or lactating women. Precautions for the elderly: The elderly are often accompanied by renal impairment, and the dosage should be reduced according to the degree of renal impairment.

This product can inhibit the normal metabolism of theophylline. When used in combination with theophylline, it can cause an abnormal increase in theophylline blood concentration and lead to poisoning or even death. Therefore, theophylline blood concentration should be monitored when the two drugs are used in combination.

Keep tightly closed in a cool, dry place.

0.1g (100,000 units)

24 months

Sancai Shiqi Pharmaceutical Co., Ltd.

• Founded in:

  2010-12-17

• Address:

  Building B, No. 1 Songbai Road, Torch Development Zone, Zhongshan City

• Tax NO.:

  91442000566655786Y

• Registered Funds:

  50 million yuan

• Email:

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