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Midecamycin Tablets

Function and Efficacy

This product is a macrolide antibiotic produced by Streptomyces mycarofaciens. It works by acting on the 50S subunit of bacterial ribosomes, inhibiting the synthesis of bacterial proteins, and is a growth-stage antibacterial drug. Its antibacterial properties are similar to those of erythromycin, and it shows strong antibacterial effects on Gram-positive bacteria and mycoplasmas, and also has antibacterial effects on some Gram-negative bacteria such as Neisseria meningitidis and Neisseria gonorrhoeae.

Ingredients

The main ingredient of this product is midecamycin. Its chemical name is [4R-(4R*,5S*,6S*,7R*,9R*,10R*,11E,13E,16R*)]-6-{[3,6-dideoxy-4-O-(2,6-dideoxy-3-carbon-methyl-a-L-ribose-hexopyranosyl)-3-(dimethylamino)-b-D-pyranoglucopyranosyl]oxy}-4,10-dihydroxy-5-methoxy-9,16-dimethyl-2-oxohexaane-11,13-diene-7-acetaldehyde 3,4-b-dipropionate.

Name Description Content CAS NO. Manufacturer
MIDECAMYCINIngredients

It works by acting on the 50S subunit of bacterial ribosomes, inhibiting the synthesis of bacterial proteins, and is a growth-stage antibacterial drug. Its antibacterial properties are similar to those of erythromycin, showing strong antibacterial effects on Gram-positive bacteria and mycoplasmas, and also on some Gram-negative bacteria such as Neisseria meningitidis and Neisseria gonorrhoeae.

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35457-80-8 2

Appearance

Gastric dissolving tablets. After removing the coating, it is white or off-white.

Indication

It is mainly suitable for respiratory tract infections and skin, soft tissue and bile tract infections caused by Staphylococcus aureus, hemolytic Streptococcus, Pneumococcus, etc., and can also be used for Mycoplasma pneumonia.

Usage and Dosage

Oral administration: 0.8-1.2g per day for adults, 30-40mg/kg per day for children according to body weight. Take in 3-4 doses.

Adverse Reactions

Gastrointestinal symptoms such as nausea, vomiting, upper abdominal discomfort, loss of appetite, etc. are occasionally seen. Transient increase in serum alanine aminotransferase is occasionally seen. Rash, urticaria and other symptoms are occasionally seen.

Precautions

Patients who are allergic to this product and macrolide drugs are contraindicated.

Special Population Medication

Precautions for children: follow doctor's advice. Precautions for pregnancy and lactation: follow doctor's advice. Precautions for the elderly: follow doctor's advice.

Drug Interactions

This product can inhibit the normal metabolism of theophylline. When used in combination with theophylline, it can cause an abnormal increase in theophylline blood concentration and lead to poisoning or even death. Therefore, theophylline blood concentration should be monitored when the two drugs are used in combination.

Storage

Keep tightly closed in a cool, dry place.

Packaging Specification

0.2g (200,000 units)

Validity Period

24 months

Manufacturer

Sancai Shiqi Pharmaceutical Co., Ltd.

  • Founded in:

    2010-12-17
  • Address:

    Building B, No. 1 Songbai Road, Torch Development Zone, Zhongshan City
  • Tax NO.:

    91442000566655786Y
  • Registered Funds:

    50 million yuan
  • Email:

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