Nefopam Hydrochloride Tablets
Function and Efficacy
This product is a new type of non-narcotic analgesic, with mild antipyretic and muscle relaxant effects. The chemical structure belongs to cyclized o-methylbenzylamine. Therefore, it does not have the characteristics of non-steroidal anti-inflammatory drugs, nor is it an opioid receptor agonist. It is effective for moderate and severe pain. An intramuscular injection of 20 mg of this product is equivalent to the effect of 12 mg of morphine. It has a mild respiratory depressant effect. It has no inhibitory effect on the circulatory system. There is no tolerance and dependence. Acute toxicity LD50 (mg/kg): mice, oral 66.6; intraperitoneal 28.7; intravenous 21.9. Rats, oral 178; intramuscular injection 56.9.
Ingredients
The main component of this product and its chemical name is: 5-methyl-1-phenyl-3,4,5,6-tetrahydro-1H-2,5-oxazolidinone hydrochloride. Its structural formula is: Molecular formula: C17H19NO·HCl Molecular weight: 289.80
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| Nefopam hydrochlorideIngredients |
This product is a new type of non-narcotic analgesic, with mild antipyretic and muscle relaxant effects. It is effective for moderate and severe pain. An intramuscular injection of 20 mg of this product is equivalent to the effect of 12 mg of morphine. It has a mild respiratory depressant effect. It has no depressant effect on the circulatory system. There is no tolerance and dependence. More |
23327-57-3 | 12 |
Appearance
This product is white tablets.
Indication
It is used for postoperative analgesia, cancer pain, acute traumatic pain, and visceral smooth muscle colic such as acute gastritis, biliary ascariasis, and ureteral stones.
Usage and Dosage
Oral: 20-60 mg once, 60-180 mg per day.
Adverse Reactions
When the effects occur, there are often drowsiness, nausea, sweating, dizziness, headache, etc. But it usually does not last long. Occasionally, dry mouth, dizziness, and rash are seen.
Precautions
It is contraindicated in patients with severe cardiovascular disease, myocardial infarction or convulsions.
Special Population Medication
Precautions for children: This experiment has not been conducted and there is no reliable reference. Precautions for pregnancy and lactation: This experiment has not been conducted and there is no reliable reference. Precautions for the elderly: This experiment has not been conducted and there is no reliable reference.
Drug Interactions
Not yet clear.
Storage
Keep away from light and store in a sealed container.
Packaging Specification
20mg
Validity Period
36 months
Manufacturer
Changchun Wande Pharmaceutical Co., Ltd.
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Founded in:
2002-01-11 -
Address:
No. 2401, Xiaonan Street, Kuancheng District, Changchun City, Jilin Province -
Tax NO.:
91220101730776820M -
Registered Funds:
12.06 million yuan -
Email: