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Tropisetron Hydrochloride Tablets

Function and Efficacy

Not yet clear.

Ingredients

The main ingredient of this product is Tropisetron Hydrochloride. Chemical name: Endo-1H-indole-3-carboxylic acid-8-methyl-8-azabicyclo[3.2.1]octan-3-yl ester hydrochloride.

Name Description Content CAS NO. Manufacturer
Tropisetron hydrochlorideIngredients

Not yet clear

More
105826-92-4 16

Appearance

This product is white tablets.

Indication

Prevention and treatment of nausea and vomiting caused by cancer chemotherapy.

Usage and Dosage

1. Children: It is generally not recommended for children. If it must be used due to medical conditions, refer to the following dosage: The dosage for children over 2 years old is 0.2 mg/L, and the maximum can reach 5 mg/day. Intravenous administration on the first day: Dissolve tropisetron hydrochloride in 100 ml of commonly used infusion solution (such as normal saline, Ringer's solution or 5% glucose solution) and quickly drip or slowly push it intravenously before chemotherapy. It can be taken orally on the 2nd to 6th day. Take an appropriate amount of tropisetron hydrochloride solution from the ampoule, dilute it with orange juice or cola, and take it immediately in the morning when you get up (at least 1 hour before breakfast). 2. Adults: The recommended dose for adults is 5 mg/day, once a day, and the course of treatment is 6 days ...

Adverse Reactions

Tropisetron hydrochloride is generally well tolerated, and adverse reactions at the recommended dose are transient. Common adverse reactions include headache, dizziness, constipation, vertigo, fatigue, and gastrointestinal disorders such as abdominal pain and diarrhea. Very few patients may experience transient blood pressure changes or allergic reactions. The former does not require special treatment, and the latter can be improved after anti-allergic treatment.

Precautions

It is contraindicated in patients allergic to tropisetron and pregnant women.

Special Population Medication

Precautions for children: It is generally not recommended. If it must be used for medical reasons, please refer to [Usage and Dosage] Precautions for pregnancy and lactation: It is forbidden for pregnant women. It has not been confirmed whether tropisetron hydrochloride is secreted into human milk, so patients taking the drug should not breastfeed. Precautions for the elderly: No dosage adjustment is required for the elderly.

Drug Interactions

1. If tropisetron hydrochloride is used simultaneously with rifampicin or other liver enzyme inducing drugs (such as phenobarbital), the plasma concentration of tropisetron hydrochloride may be reduced. Therefore, patients with normal metabolism need to increase the dose (patients with poor metabolism do not need to increase the dose). 2. The effect of cytochrome P450 enzyme inhibitors such as cimetidine on the plasma concentration of tropisetron hydrochloride can be ignored. Under normal use, there is no need to adjust the dose.

Storage

seal.

Packaging Specification

5 mg (as tropisetron)

Validity Period

12 months

Manufacturer

Kinhoo Pharmaceutical Co., Ltd.

  • Founded in:

    2005-04-18
  • Address:

    Zhuhai Golden Coast Bio-Industrial Zone
  • Tax NO.:

    914404007740042759
  • Registered Funds:

    65.6 million yuan
  • Website:

  • Email:

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