Compound dihydralazine sulfate tablets
Function and Efficacy
1. Blood pressure reduction. The exact mechanism of blood pressure reduction of this product is unknown. It mainly dilates arterioles, with little effect on veins, reducing peripheral vascular resistance, increasing heart rate, and increasing stroke volume and cardiac output. Long-term use can increase renin secretion, aldosterone, and water and sodium retention, thereby reducing the effect. 2. Heart failure. This product increases cardiac output and reduces vascular resistance and afterload.
Ingredients
The chemical name of this product is: 1,4-dihydrazino-2,3-naphthylidene sulfate dihydrate. Its structural formula is: Molecular formula: C8H10N6H2SO42H2O Molecular weight: 333.32
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| Dihydralazine sulphateIngredients |
1. Blood pressure reduction: mainly dilates arterioles, has little effect on veins, reduces peripheral vascular resistance, increases heart rate, and increases stroke volume and cardiac output. Long-term use can increase renin secretion, aldosterone, and water and sodium retention, which reduces the effect. 2. Heart failure: increases cardiac output, reduces vascular resistance and afterload. More |
7327-87-9 | 9 |
Appearance
This product is white or slightly yellow crystalline powder, and its anhydrous form is yellow powder.
Indication
Used to treat high blood pressure or heart failure.
Usage and Dosage
The usual oral dose for adults is 12.5-25 mg each time, 3 times a day. Later, it can be increased to 50 mg each time, 3 times a day as needed.
Adverse Reactions
1. Common adverse reactions include: diarrhea, palpitations, tachycardia, headache, vomiting, nausea. 2. Rare adverse reactions include: constipation, hypotension, facial flushing, tearing, nasal congestion. 3. Rare adverse reactions include: rash, itching, chest pain, lymphadenopathy, peripheral neuritis, edema, systemic lupus erythematosus caused by immune allergy.
Precautions
Patients with aortic aneurysm, stroke, and severe renal dysfunction should be considered contraindications.
Special Population Medication
Precautions for children: This has not been implemented and there are no reliable references. Precautions for pregnancy and lactation: This product can pass through the placenta and be secreted through breast milk. Therefore, it is forbidden for pregnant and lactating women. Precautions for the elderly: The elderly are more sensitive to the antihypertensive effect of this product. During the period of taking it, the dosage or frequency of taking the medicine should be appropriately reduced according to the blood pressure situation.
Drug Interactions
1. When used with nonsteroidal anti-inflammatory analgesics, the antihypertensive effect may be weakened. 2. When used with sympathomimetic amines, the antihypertensive effect of this product may be reduced. 3. When used with diazoxide or other antihypertensive drugs, the antihypertensive effect may be enhanced.
Storage
Keep away from light and store in sealed container.
Packaging Specification
Compound
Validity Period
Tentative 24 months
Manufacturer
Changzhou Pharmaceutical Factory Co., Ltd.
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Founded in:
2001-12-14 -
Address:
No. 518, Laodong East Road, Changzhou -
Tax NO.:
91320400137158490L -
Registered Funds:
108 million yuan -
Website:
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Email: