Ursodeoxycholic acid tablets
Function and Efficacy
Ursodeoxycholic acid accounts for a small part of human bile. After oral administration of ursodeoxycholic acid, the cholesterol saturation in bile is reduced by inhibiting the reabsorption of cholesterol in the intestine and reducing the secretion of cholesterol into bile. Cholesterol stones are gradually dissolved, probably due to the dispersion of cholesterol and the formation of liquid crystals. According to existing knowledge, the treatment of liver and cholestatic diseases with ursodeoxycholic acid capsules is mainly based on the relative replacement of lipophilic, detergent-like toxic bile acids by hydrophilic, cytoprotective and non-cytotoxic ursodeoxycholic acid, as well as the promotion of hepatocyte secretion and immunomodulation.
Ingredients
The main ingredient of this product is ursodeoxycholic acid. Its chemical name is 3alpha,7beta-dihydroxy-5beta-cholestane-24-acid.
| Name | Description | Content | CAS NO. | Manufacturer |
|---|---|---|---|---|
| Ursodeoxycholic acidIngredients |
By inhibiting the reabsorption of cholesterol in the intestine and reducing the secretion of cholesterol into the bile, the saturation of cholesterol in the bile is reduced. Cholesterol stones may be gradually dissolved due to the dispersion of cholesterol and the formation of liquid crystals. The treatment of liver and cholestatic diseases is mainly based on the relative replacement of lipophilic, detergent-like toxic bile acids by hydrophilic, cytoprotective and non-cytotoxic ursodeoxycholic acid, as well as the promotion of hepatocyte secretion and immunomodulation. More |
128-13-2 | 39 |
Appearance
Ursodeoxycholic acid is a white crystalline powder, odorless and bitter. It is almost insoluble in water, easily soluble in ethanol and glacial acetic acid, slightly soluble in imitation, and very slightly soluble in ether. This product is a white tablet.
Indication
This product is used for cholesterol gallstone formation and bile-deficient steatorrhea. It can also be used to prevent drug-induced stone formation and treat steatorrhea (after ileal resection).
Usage and Dosage
Adult oral administration: 8-10 mg/kg daily, divided into two doses during the morning and evening meals. The shortest course of treatment is 6 months. If there is no improvement in ultrasound examination and cholecystography after 6 months, the drug can be discontinued; if the stones have partially dissolved, continue to take the drug until the stones are completely dissolved.
Adverse Reactions
The toxicity and side effects of this product are less than those of chenodeoxycholic acid. It generally does not cause diarrhea. Other occasional adverse reactions include constipation, allergies, headaches, dizziness, pancreatitis, and tachycardia. During the treatment period, it may cause calcification of gallstones and soft stools.
Precautions
Acute biliary infection, biliary obstruction, pregnant and lactating women.
Special Population Medication
Precautions for children: Precautions for pregnancy and lactation: Precautions for pregnant and lactating women: Precautions for the elderly: Use with caution in elderly patients.
Drug Interactions
1. Contraceptive pills can increase bile saturation. When using this product for treatment, other birth control measures should be taken as much as possible to avoid affecting the efficacy. 2. Cholestyramine (Cholestyramine), colestipol (Colestipol) and aluminum-containing antacids can bind to CDCA and reduce its absorption, so they should not be used together.
Storage
Keep away from light and sealed
Packaging Specification
50mg
Validity Period
24 months
Manufacturer
Guangdong Eashu Pharmaceutical Co., Ltd.
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Founded in:
2000-10-09 -
Address:
No. 6, Fenggang West Street, Zhaoqing High-tech Zone, Guangdong Province -
Tax NO.:
914412007254731393 -
Registered Funds:
87.710778 million yuan -
Website:
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Email: