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Lipoic Acid Injection

Function and Efficacy

This product is widely used to treat diabetic neuropathy. In vitro tests show that this product can reduce lipid oxidation in nerve tissue, and it may prevent the glycosylation of proteins; it can inhibit aldose reductase, thereby preventing the conversion of glucose or galactose into sorbitol, so lipoic acid can prevent diabetes, control blood sugar, and prevent neuropathy caused by high blood sugar. Lipoic acid is a powerful antioxidant whether in a water-soluble matrix or an oil-soluble matrix. Both lipoic acid and its reduced form of dihydrolipoic acid can exert antioxidant effects. They can directly or indirectly promote the regeneration of vitamin C and vitamin E in the body. Studies have shown that lipoic acid can increase the levels of glutathione and coenzyme Q10 in cells. Lipoic acid can chelate certain metal ions

Ingredients

(±)-5-[3-(1,2-Dithiolane)]-pentanoic acid

Appearance

This product is light yellow clear liquid.

Indication

Paresthesias caused by diabetic peripheral neuropathy.

Usage and Dosage

This product can be used for intravenous injection. Intravenous injection should be slow, with a maximum speed of 50 mg lipoic acid per minute (equivalent to 2 ml of this injection). This product can also be added to normal saline for intravenous drip, such as 250-500 mg lipoic acid (equivalent to 10-20 ml of this injection) added to 100-250 ml of normal saline, and the intravenous drip time is about 30 minutes. Unless otherwise prescribed by a doctor, patients with sensory abnormalities caused by severe diabetic peripheral neuropathy can be given intravenous drip, 300-600 mg (equivalent to 12-24 ml of this injection) per day, and a course of treatment is 2-4 weeks.

Adverse Reactions

Too fast intravenous infusion may occasionally cause headache and dyspnea, but they can be relieved by themselves. After using this product, very few patients have convulsions, diplopia, purpura, and bleeding tendency caused by abnormal platelet function. There are very few case reports of allergy to benzyl alcohol in this product.

Precautions

People who are allergic to this product.

Special Population Medication

Precautions for children: This injection contains benzyl alcohol, so it cannot be used for newborns, especially premature infants, and is prohibited for intramuscular injection in children. Precautions for pregnancy and lactation: Pregnant and lactating women should not use this product. Precautions for the elderly: No special dosage adjustment is required clinically.

Drug Interactions

This product may inhibit the efficacy of cisplatin.

Storage

This product should be stored below 25℃ and away from light in a box. The validity period is 18 months.

Packaging Specification

12ml:0.3g

Validity Period

18 months.

Manufacturer

Dandong Yichuang Pharmaceutical Co., Ltd.

  • Founded in:

    2003-12-30
  • Address:

    No. 6, Yongxiang Street, Donggang City, Dandong City, Liaoning Province
  • Tax NO.:

    9121060075578371X5
  • Registered Funds:

    7.142857 million yuan
  • Website:

  • Email:

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