UREA- urea_cream
Function and Efficacy
Clinical Pharmacology
Urea gently dissolves the intracellular matrix which results in loosening of the horny layer of the skin and shedding of scaly skin at regular intervals, thereby softening hyperkeratotic areas of the skin.
Pharmacokinetics
The mechanism of action of topically applied urea is not yet known.
Indication
For debridement and promotion of normal healing of hyperkeratotic surface lesions, particularly where healing is retarded by local infection, necrotic tissue, fibrinous or purulent debris or eschar. Urea is useful for the treatment of hyperkeratotic conditions such as dry, rough skin, dermatitis, psoriasis, xerosis, ichthyosis, eczema, keratosis pilaris, keratosis palmaris, keratoderma, corns and calluses, as well as damaged, ingrown and devitalized nails.
Usage and Dosage
Apply Urea 40% to affected skin twice per day, or as directed by your physician. Rub in until completely absorbed.
Label
Adverse Reactions
Transient stinging, burning, itching or irritation may occur and normally disappear upon discontinuing the medication. To report SUSPECTED ADVERSE REACTIONS contact AvKARE at 1-855-361-3993; email drugsafety@avkare.com ; or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch
Precautions
Known hypersensitivity to any of the listed ingredients.
Other Information
For topical use only. Avoid contact with eyes, lips or mucous membranes.
Manufacturer
AvPAK